Graziella Curtale
Overview
Explore the profile of Graziella Curtale including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
1418
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Locati M, Curtale G, Mantovani A
Annu Rev Pathol
. 2019 Sep;
15:123-147.
PMID: 31530089
Macrophages are a diverse set of cells present in all body compartments. This diversity is imprinted by their ontogenetic origin (embryonal versus adult bone marrow-derived cells); the organ context; by...
2.
Curtale G, Rubino M, Locati M
Front Immunol
. 2019 May;
10:799.
PMID: 31057539
The efficacy of macrophage- mediated inflammatory response relies on the coordinated expression of key factors, which expression is finely regulated at both transcriptional and post-transcriptional level. Several studies have provided...
3.
Curtale G, Renzi T, Mirolo M, Drufuca L, Albanese M, De Luca M, et al.
Front Immunol
. 2018 Sep;
9:2037.
PMID: 30245693
An appropriate immune response requires a tight balance between pro- and anti-inflammatory mechanisms. IL-10 is induced at late time-points during acute inflammatory conditions triggered by TLR-dependent recognition of infectious agents...
4.
Curtale G
Cells
. 2018 Feb;
7(2).
PMID: 29419779
Innate immune cells form an integrative component of the tumor microenvironment (TME), which can control or prevent tumor initiation and progression, due to the simultaneous processing of both anti- and...
5.
Curtale G, Renzi T, Drufuca L, Rubino M, Locati M
Eur J Immunol
. 2017 Aug;
47(12):2080-2089.
PMID: 28776644
Endotoxin tolerance assures proper regulation of the TLR4 signaling pathway and avoids uncontrolled inflammation, limiting tissue damage and endotoxin shock development. Though underlying molecular mechanisms are still undefined, evidence indicates...
6.
Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, et al.
Elife
. 2017 May;
6.
PMID: 28464980
The Hippo-YAP pathway is a central regulator of cell contact inhibition, proliferation and death. There are conflicting reports regarding the role of Angiomotin (Amot) in regulating this pathway. While some...
7.
Renzi T, Rubino M, Gornati L, Garlanda C, Locati M, Curtale G
Mediators Inflamm
. 2015 Oct;
2015:145305.
PMID: 26451077
A proper regulation of the innate immune response is fundamental to keep the immune system in check and avoid a chronic status of inflammation. As they act as negative modulators...
8.
Curtale G, Citarella F
Int J Mol Sci
. 2013 Aug;
14(9):17347-77.
PMID: 23975170
Immune response plays a fundamental role in protecting the organism from infections; however, dysregulation often occurs and can be detrimental for the organism, leading to a variety of immune-mediated diseases....
9.
Curtale G, Mirolo M, Renzi T, Rossato M, Bazzoni F, Locati M
Proc Natl Acad Sci U S A
. 2013 Jun;
110(28):11499-504.
PMID: 23798430
Toll-like receptors (TLRs) play key roles in detecting pathogens and initiating inflammatory responses that, subsequently, prime specific adaptive responses. Several mechanisms control TLR activity to avoid excessive inflammation and consequent...
10.
Rossato M, Curtale G, Tamassia N, Castellucci M, Mori L, Gasperini S, et al.
Proc Natl Acad Sci U S A
. 2012 Oct;
109(45):E3101-10.
PMID: 23071313
IL-10 is a potent anti-inflammatory molecule that, in phagocytes, negatively targets cytokine expression at transcriptional and posttranscriptional levels. Posttranscriptional checkpoints also represent the specific target of a recently discovered, evolutionary...