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Grant Sellar

Explore the profile of Grant Sellar including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 87
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Recent Articles
1.
Langdon S, Kay C, Um I, Dodds M, Muir M, Sellar G, et al.
Sci Rep . 2019 Dec; 9(1):18742. PMID: 31822716
This study investigated the antitumour effects of two dual mTOR/PI3K inhibitors, gedatolisib (WYE-129587/PKI-587/PF-05212384) and PF-04691502 against a panel of six human patient derived ovarian cancer xenograft models. Both dual mTOR/PI3K...
2.
Mudaliar M, Haggart R, Miele G, Sellar G, Tan K, Goodlad J, et al.
PLoS One . 2013 Sep; 8(9):e72591. PMID: 24023754
We present the first comparison of global transcriptional changes in canine and human diffuse large B-cell lymphoma (DLBCL), with particular reference to the nuclear factor-kappa B (NF-κB) pathway. Microarray data...
3.
Heys S, Stewart K, McKenzie E, Miller I, Wong S, Sellar G, et al.
Breast Cancer Res Treat . 2012 Aug; 135(2):539-48. PMID: 22886449
The role of the tumour microenvironment and complex cellular interactions has attracted interest in responses to primary chemotherapy. Of particular interest are tumour-infiltrating T cells and tumour-infiltrating macrophages (TIMs). We...
4.
Sellar G, Alvarez J, Loganzo F, Abbas R, Immermann F, Karnoub M, et al.
Biomark Med . 2010 May; 2(2):147-53. PMID: 20477436
An area of unmet medical need in clinical oncology has been optimizing patient selection for a given therapeutic with the goal of getting the right drug to the right patient....
5.
Atrih A, Turnock D, Sellar G, Thompson A, Feuerstein G, Ferguson M, et al.
J Proteome Res . 2009 Nov; 9(2):743-51. PMID: 19902931
The Ptdlns-3-kinase (PI3-K) signaling pathway plays a vital role in cell survival, proliferation, apoptosis and differentiation in normal cells, as well as in diseases such as cancer and diabetes. Quantification...