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David J Argyle

Explore the profile of David J Argyle including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 856
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Ward C, Meehan J, Gray M, Murray A, Argyle D, Kunkler I, et al.
Explor Target Antitumor Ther . 2022 Sep; 1(2):71-100. PMID: 36046070
Dysregulation of cellular pH is frequent in solid tumours and provides potential opportunities for therapeutic intervention. The acidic microenvironment within a tumour can promote migration, invasion and metastasis of cancer...
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Ferrari G, Pang L, de Moliner F, Vendrell M, Reardon R, Higgins A, et al.
Cancers (Basel) . 2022 Feb; 14(4). PMID: 35205831
Bleomycin is a chemotherapy agent that, when administered systemically, can cause severe pulmonary toxicity. Bleosome is a novel formulation of bleomycin encapsulated in ultra-deformable (UD) liposomes that may be applicable...
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Payton C, Pang L, Gray M, Argyle D
J Pers Med . 2021 Dec; 11(12). PMID: 34945782
Radiation resistance is a significant challenge in the treatment of breast cancer in humans. Human breast cancer is commonly treated with surgery and adjuvant chemotherapy/radiotherapy, but recurrence and metastasis upon...
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Ikeh K, Lamkin E, Crompton A, Deutsch J, Fisher K, Gray M, et al.
Cancers (Basel) . 2021 Nov; 13(21). PMID: 34771454
Cancer therapy resistance is a persistent clinical challenge. Recently, inhibition of the mutagenic translesion synthesis (TLS) protein REV1 was shown to enhance tumor cell response to chemotherapy by triggering senescence...
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Gonzalez-Fernandez E, Staderini M, Marland J, Gray M, Ucar A, Dunare C, et al.
Biosens Bioelectron . 2021 Nov; 197:113728. PMID: 34763151
The development of robust implantable sensors is important in the successful advancement of personalised medicine as they have the potential to provide in situ real-time data regarding the status of...
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Silveira T, Pang L, Di Domenico A, Veloso E, Silva I, Del Puerto H, et al.
Front Vet Sci . 2021 Sep; 8:633170. PMID: 34513965
Metastatic melanoma is a very aggressive form of cancer in both humans and dogs. Dogs primarily develop oral melanoma of mucosal origin. Although oral melanoma in humans is rare, both...
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Marland J, Gray M, Argyle D, Underwood I, Murray A, Potter M
Micromachines (Basel) . 2021 Aug; 12(7). PMID: 34357220
Anastomotic leakage (AL) is a common and dangerous post-operative complication following intestinal resection, causing substantial morbidity and mortality. Ischaemia in the tissue surrounding the anastomosis is a major risk-factor for...
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Gray M, Marland J, Murray A, Argyle D, Potter M
J Pers Med . 2021 Jun; 11(6). PMID: 34070593
Development of an anastomotic leak (AL) following intestinal surgery for the treatment of colorectal cancers is a life-threatening complication. Failure of the anastomosis to heal correctly can lead to contamination...