Graham K Sheridan
Overview
Explore the profile of Graham K Sheridan including associated specialties, affiliations and a list of published articles.
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30
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1112
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Recent Articles
1.
Magalhaes D, Stewart N, Mampay M, Rolle S, Hall C, Moeendarbary E, et al.
J Neurochem
. 2024 Feb;
168(6):1113-1142.
PMID: 38339785
The small-molecule drug, FTY720 (fingolimod), is a synthetic sphingosine 1-phosphate (S1P) analogue currently used to treat relapsing-remitting multiple sclerosis in both adults and children. FTY720 can cross the blood-brain barrier...
2.
Magalhaes D, Mampay M, Sebastiao A, Sheridan G, Valente C
Neurochem Int
. 2024 Jan;
174:105678.
PMID: 38266657
Social isolation is a chronic mild stressor and a significant risk factor for mental health disorders. Herein we explored the impact of social isolation on depression- and anxiety-like behaviours, as...
3.
Hall C, Lasli S, Serwinski B, Djordjevic B, Sheridan G, Moeendarbary E
Front Aging Neurosci
. 2023 Sep;
15:1273549.
PMID: 37700816
[This corrects the article DOI: 10.3389/fnagi.2023.1212212.].
4.
Whisler J, Shahreza S, Schlegelmilch K, Ege N, Javanmardi Y, Malandrino A, et al.
Sci Adv
. 2023 Aug;
9(32):eadg9781.
PMID: 37566656
Vascularization is driven by morphogen signals and mechanical cues that coordinately regulate cellular force generation, migration, and shape change to sculpt the developing vascular network. However, it remains unclear whether...
5.
Hall C, Lasli S, Serwinski B, Djordjevic B, Sheridan G, Moeendarbary E
Front Aging Neurosci
. 2023 Aug;
15:1212212.
PMID: 37547743
Widespread neurodegeneration, enlargement of cerebral ventricles, and atrophy of cortical and hippocampal brain structures are classic hallmarks of Alzheimer's disease (AD). Prominent macroscopic disturbances to the cytoarchitecture of the AD...
6.
Javanmardi Y, Agrawal A, Malandrino A, Lasli S, Chen M, Shahreza S, et al.
Adv Sci (Weinh)
. 2023 Apr;
10(16):e2206554.
PMID: 37051804
Cancer cell extravasation, a key step in the metastatic cascade, involves cancer cell arrest on the endothelium, transendothelial migration (TEM), followed by the invasion into the subendothelial extracellular matrix (ECM)...
7.
Esteki M, Malandrino A, Alemrajabi A, Sheridan G, Charras G, Moeendarbary E
iScience
. 2021 Dec;
24(12):103482.
PMID: 34927026
Cells maintain their volume through fine intracellular osmolarity regulation. Osmotic challenges drive fluid into or out of cells causing swelling or shrinkage, respectively. The dynamics of cell volume changes depending...
8.
Mampay M, Flint M, Sheridan G
Br J Pharmacol
. 2021 May;
178(19):3977-3996.
PMID: 34029379
People that develop extracranial cancers often display co-morbid neurological disorders, such as anxiety, depression and cognitive impairment, even before commencement of chemotherapy. This suggests bidirectional crosstalk between non-CNS tumours and...
9.
Lizarraga-Valderrama L, Sheridan G
FEBS Lett
. 2021 Mar;
595(10):1391-1410.
PMID: 33728650
Neurons and glial cells of the central nervous system (CNS) release extracellular vesicles (EVs) to the interstitial fluid of the brain and spinal cord parenchyma. EVs contain proteins, nucleic acids...
10.
Mampay M, Velasco-Estevez M, Rolle S, Chaney A, Boutin H, Dev K, et al.
FEBS Open Bio
. 2020 Nov;
11(1):146-163.
PMID: 33185010
In the brain, REST (Repressor Element-1 Silencing Transcription factor) is a key regulator of neuron cell-specific gene expression. Nuclear translocation of neuronal REST has been shown to be neuroprotective in...