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Graham Heap

Explore the profile of Graham Heap including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 805
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Recent Articles
1.
Armstrong A, Gooderham M, Lynde C, Maari C, Forman S, Green L, et al.
JAMA Dermatol . 2024 Aug; 160(10):1066-1074. PMID: 39167366
Importance: New, effective, and well-tolerated oral therapies are needed for treating psoriasis. Zasocitinib, a highly selective allosteric tyrosine kinase 2 (TYK2) inhibitor, is a potential new oral treatment for this...
2.
Rivas M, Avila B, Koskela J, Huang H, Stevens C, Pirinen M, et al.
PLoS Genet . 2019 May; 15(5):e1008190. PMID: 31145742
[This corrects the article DOI: 10.1371/journal.pgen.1007329.].
3.
Rivas M, Avila B, Koskela J, Huang H, Stevens C, Pirinen M, et al.
PLoS Genet . 2018 May; 14(5):e1007329. PMID: 29795570
As part of a broader collaborative network of exome sequencing studies, we developed a jointly called data set of 5,685 Ashkenazi Jewish exomes. We make publicly available a resource of...
4.
de Lange K, Moutsianas L, Lee J, Lamb C, Luo Y, Kennedy N, et al.
Nat Genet . 2017 Jan; 49(2):256-261. PMID: 28067908
Genetic association studies have identified 215 risk loci for inflammatory bowel disease, thereby uncovering fundamental aspects of its molecular biology. We performed a genome-wide association study of 25,305 individuals and...
5.
Dinesen L, Walsh A, Nedeljkovic Protic M, Heap G, Cummings F, Warren B, et al.
J Crohns Colitis . 2010 Dec; 4(4):431-7. PMID: 21122540
Background: The prognosis of acute severe ulcerative colitis (ASC) influences therapeutic decisions, but data on prevalence or long-term outcome are few. Methods: A systematic review of all patients with UC...