Graham A R Heap
Overview
Explore the profile of Graham A R Heap including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
1311
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Recent Articles
1.
Hunt K, Smyth D, Balschun T, Ban M, Mistry V, Ahmad T, et al.
Nat Genet
. 2011 Dec;
44(1):3-5.
PMID: 22200769
No abstract available.
2.
Trynka G, Hunt K, Bockett N, Romanos J, Mistry V, Szperl A, et al.
Nat Genet
. 2011 Nov;
43(12):1193-201.
PMID: 22057235
Using variants from the 1000 Genomes Project pilot European CEU dataset and data from additional resequencing studies, we densely genotyped 183 non-HLA risk loci previously associated with immune-mediated diseases in...
3.
Dubois P, Trynka G, Franke L, Hunt K, Romanos J, Curtotti A, et al.
Nat Genet
. 2010 Mar;
42(4):295-302.
PMID: 20190752
We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS) < 10(-4) and 18 SNPs...
4.
L E Koskinen L, Einarsdottir E, Dukes E, Heap G, Dubois P, Korponay-Szabo I, et al.
Hum Mol Genet
. 2008 Dec;
18(6):1148-55.
PMID: 19103669
Coeliac disease is caused by dietary gluten, triggering a chronic inflammation of the small intestine in genetically predisposed individuals. Recently, a risk locus on chromosome 2q11-q12, harbouring interleukin 18 receptor...
5.
Hunt K, Zhernakova A, Turner G, Heap G, Franke L, Bruinenberg M, et al.
Nat Genet
. 2008 Mar;
40(4):395-402.
PMID: 18311140
Our genome-wide association study of celiac disease previously identified risk variants in the IL2-IL21 region. To identify additional risk variants, we genotyped 1,020 of the most strongly associated non-HLA markers...