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Graham A Mackay

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Articles 18
Citations 165
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Recent Articles
1.
Ding J, Zhang S, Fernandopulle N, Karas J, Li J, Ziogas J, et al.
Eur J Pharmacol . 2024 Oct; 984:177050. PMID: 39389528
The emergence of multi-drug resistant Gram-negative bacteria has led to renewed interest in the antimicrobial activity of polymyxins and novel polymyxin analogues (e.g. nonapeptides and octapeptin). In some individuals, clinically...
2.
Ding J, Hillig C, White C, Fernandopulle N, Anderton H, Kern J, et al.
Allergy . 2024 Jan; 79(6):1609-1612. PMID: 38279626
No abstract available.
3.
McComish J, Slade C, Buizen L, Paul S, Chatelier J, Unglik G, et al.
J Allergy Clin Immunol Pract . 2023 Apr; 11(7):2248-2250.e3. PMID: 37088371
No abstract available.
4.
Hsin L, Fernandopulle N, Ding J, Lumb C, Veldhuis N, Karas J, et al.
Pharmacol Res Perspect . 2022 Jul; 10(4):e00990. PMID: 35904495
The tachykinin neuropeptide substance P (SP) is the canonical agonist peptide for the neurokinin 1 receptor (NK R). More recently, it has also been shown to activate the Mas-related G...
5.
Mackay G, Fernandopulle N, Ding J, McComish J, Soeding P
Front Immunol . 2021 Dec; 12:688930. PMID: 34867939
Acute anaphylaxis to small molecule drugs is largely considered to be antibody-mediated with immunogloblin E (IgE) and mast cell activation being key. More recently, a role for drug-reactive immunoglobulin G...
6.
Wines B, Trist H, Esparon S, Impey R, Mackay G, Andrews R, et al.
Front Immunol . 2021 Nov; 12:666813. PMID: 34759915
FcγR activity underpins the role of antibodies in both protective immunity and auto-immunity and importantly, the therapeutic activity of many monoclonal antibody therapies. Some monoclonal anti-FcγR antibodies activate their receptors,...
7.
Fernandopulle N, Zhang S, Soeding P, Mackay G
Clin Exp Allergy . 2020 Dec; 51(5):685-695. PMID: 33275825
Background: Neuromuscular-blocking agents (NMBAs) can cause both IgE-dependent and IgE-independent anaphylactic reactions, with activation of the mast cell receptor MRGPRX2 being important to the latter. Sugammadex, a reversal agent for...
8.
Cammaert L, Macleod A, Mackay G, Duncan C
Neurology . 2019 Sep; 93(10):459-460. PMID: 31477611
No abstract available.
9.
Anania J, Trist H, Palmer C, Tan P, Kouskousis B, Chenoweth A, et al.
Front Immunol . 2018 Sep; 9:1809. PMID: 30177930
FcγRIIa is an activating FcγR, unique to humans and non-human primates. It induces antibody-dependent proinflammatory responses and exists predominantly as FcγRIIa1. A unique splice variant, we designated FcγRIIa3, has been...
10.
Kuek L, Griffin P, Martinello P, Graham A, Kalitsis P, Robinson P, et al.
Am J Respir Cell Mol Biol . 2018 Feb; 59(3):375-382. PMID: 29481304
Primary ciliary dyskinesia is an inherited, currently incurable condition. In the respiratory system, primary ciliary dyskinesia causes impaired functioning of the mucociliary escalator, leading to nasal congestion, cough, and recurrent...