Gordon Beck
Overview
Explore the profile of Gordon Beck including associated specialties, affiliations and a list of published articles.
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5
Citations
241
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Recent Articles
1.
Khan A, Benboubetra M, Sayyed P, Ng K, Fox S, Beck G, et al.
J Drug Target
. 2004 Nov;
12(6):393-404.
PMID: 15545089
Small interfering RNA (siRNA), antisense oligonucleotides (ODNs), ribozymes and DNAzymes have emerged as sequence-specific inhibitors of gene expression that may have therapeutic potential in the treatment of a wide range...
2.
Higgins B, Kolinsky K, Smith M, Beck G, Rashed M, Adames V, et al.
Anticancer Drugs
. 2004 May;
15(5):503-12.
PMID: 15166626
Our objective was the preclinical assessment of the pharmacokinetics, monotherapy and combined antitumor activity of the epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor erlotinib in athymic nude mice bearing...
3.
Zhao Y, Abraham M, Le J, Hersey A, Luscombe C, Beck G, et al.
Eur J Med Chem
. 2003 Apr;
38(3):233-43.
PMID: 12667690
The absorption of 111 drug and drug-like compounds was evaluated from 111 references based on the ratio of urinary excretion of drugs following oral and intravenous administration to intact rats...
4.
Zhao Y, Abraham M, Le J, Hersey A, Luscombe C, Beck G, et al.
Pharm Res
. 2002 Nov;
19(10):1446-57.
PMID: 12425461
Purpose: To classify the dissolution and diffusion rate-limited drugs and establish quantitative relationships between absorption and molecular descriptors. Methods: Absorption consists of kinetic transit processes in which dissolution, diffusion, or...
5.
Abraham M, Zhao Y, Le J, Hersey A, Luscombe C, Reynolds D, et al.
Eur J Med Chem
. 2002 Jul;
37(7):595-605.
PMID: 12126778
In order to investigate whether the main step in intestinal absorption in humans is dominated by partition or by diffusion, we have transformed % human intestinal absorption into a first-order...