Gopal Pandit
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Explore the profile of Gopal Pandit including associated specialties, affiliations and a list of published articles.
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12
Citations
71
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Recent Articles
1.
Sarkar T, Ghosh S, Kumar Sundaravadivelu P, Pandit G, Debnath S, Thummer R, et al.
ACS Infect Dis
. 2024 Jan;
10(2):562-581.
PMID: 38294842
Antimicrobial peptides (AMPs) have been an alternate promising class of therapeutics in combating global antibiotic resistance threat. However, the short half-life of AMPs, owing to protease degradability, is one of...
2.
Pandit G, Sarkar T, S R V, Debnath S, Satpati P, Chatterjee S
ACS Omega
. 2022 May;
7(18):15951-15968.
PMID: 35571791
Rapidly growing antimicrobial resistance (AMR) against antibiotics has propelled the development of synthetic antimicrobial peptides (AMPs) as potential antimicrobial agents. An antimicrobial peptide Nle-Dab-Trp-Nle-Dab-Dab-Nle-CONH (; Nle = norleucine, Dab =...
3.
Ghosh S, Pandit G, Debnath S, Chatterjee S, Satpati P
RSC Adv
. 2022 May;
11(58):36836-36849.
PMID: 35494385
Recently, we reported a cationic 14 residue peptide LL-14 (LKWLKKLLKWLKKL) with salt-sensitive broad-spectrum antimicrobial potency. However, the mechanism of its salt (NaCl) sensitivity remained unclear. In this study, we have...
4.
Roy K, Pandit G, Chetia M, Sarkar A, Chowdhuri S, Bidkar A, et al.
ACS Appl Bio Mater
. 2022 Jan;
3(9):6251-6262.
PMID: 35021757
A charged synthetic peptide-based noncytotoxic hydrogelator was employed in encapsulation, storage, and sustainable release of different kinds of drugs, namely, ciprofloxacin (CP), an antibiotic; 5-fluorouracil (5-FU), an anticancer drug and...
5.
Debnath S, Ghosh S, Pandit G, Satpati P, Chatterjee S
J Org Chem
. 2021 Sep;
86(17):11310-11323.
PMID: 34479402
The effect of insertion of three geminally dimethyl substituted γ amino acid residues [γ (4-amino-2,2-dimethylbutanoic acid), γ (4-amino-3,3-dimethylbutanoic acid), and γ (4-amino-4,4-dimethylbutanoic acid)] at the ( + 2) position of...
6.
Pandit G, Chowdhury N, Abdul Mohid S, Bidkar A, Bhunia A, Chatterjee S
ChemMedChem
. 2020 Oct;
16(2):355-367.
PMID: 33026188
Herein we report the efficacy and toxicity of three de novo designed cationic antimicrobial peptides (AMPs) LL-14, VV-14 and ββ-14, where side chains of the hydrophobic amino acids were reduced...
7.
Pandit G, Biswas K, Ghosh S, Debnath S, Bidkar A, Satpati P, et al.
Biochim Biophys Acta Biomembr
. 2020 Jan;
1862(4):183177.
PMID: 31954105
The widespread abuse of antibiotics has led to the use of antimicrobial peptides (AMPs) as a replacement for the existing conventional therapeutic agents for combating microbial infections. The broad-spectrum activity...
8.
Pegu R, Pandit G, Guha A, Das S, Pratihar S
Spectrochim Acta A Mol Biomol Spectrosc
. 2018 Dec;
211:246-253.
PMID: 30553994
In this report, 6H-indolo[2,3-b]quinoline (hereafter 2a) was synthesized and employed as an optical chemosensor for fluoride. The sensitivity of 2a towards fluoride was established from the change in both the...
9.
Pandit G, Ilyas H, Ghosh S, Bidkar A, Abdul Mohid S, Bhunia A, et al.
J Med Chem
. 2018 Aug;
61(17):7614-7629.
PMID: 30070835
Antimicrobial peptides have gained widespread attention as an alternative to the conventional antibiotics for combating microbial infections. Here, we report a detailed structure-function correlation of two nontoxic, nonhemolytic, and salt-tolerant...
10.
Pandit G, Roy K, Agarwal U, Chatterjee S
ACS Omega
. 2018 Jul;
3(3):3143-3155.
PMID: 30023862
We report the mechanism of the concentration-dependent self-assembly of a tetrapeptide. Peptide Boc-Trp-Leu-Trp-Leu-OMe self-assembles to form discrete nanospheres at a low concentration. Tryptophan side chains point outwards of the nanospheres...