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Gobalakrishnan Sundaresan

Explore the profile of Gobalakrishnan Sundaresan including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 791
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Recent Articles
1.
Cai Q, Kim M, Harada A, Idowu M, Sundaresan G, Zweit J, et al.
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430216
Colitis-associated colon cancer (CAC) accompanies the massive infiltration of neutrophils during tumorigenesis and progression of CAC. Depletion of neutrophils in circulation results in significant inhibition of tumor incidence in CAC....
2.
Leslie S, Nicolini A, Sundaresan G, Zweit J, Boyan B, Schwartz Z
J Mater Chem B . 2020 Apr; 4(20):3515-3525. PMID: 32263385
Alginate microbeads incorporating adipose-derived stem cells (ASCs) have potential for delivering viable cells capable of facilitating tissue regeneration. These microbeads are formed in calcium crosslinking solutions containing organic osmolytes to...
3.
Sun M, Sundaresan G, Jose P, Yang L, Hoffman D, Lamichhane N, et al.
J Mater Chem B . 2020 Apr; 2(28):4456-4466. PMID: 32261547
Here we describe a novel strategy to incorporate indium-111 into near infrared (NIR) emitting Cu-In-Se quantum dots (CIS-QDs) to synthesize intrinsically radiolabeled QDs (rQDs), as a quantitative tool for in...
4.
Yang L, Sundaresan G, Sun M, Jose P, Hoffman D, McDonagh P, et al.
J Mater Chem B . 2020 Apr; 1(10):1421-1431. PMID: 32260782
Cerium oxide nanoparticles (CONPs) have demonstrated protection properties against oxidation in various cells and tissues. The mechanism of this, however, is poorly understood. Monitoring the interaction of CONPs with biological...
5.
Krzastek S, Goliadze E, Zhou S, Petrossian A, Youniss F, Sundaresan G, et al.
Cancer Immunol Immunother . 2018 Jun; 67(12):1939-1947. PMID: 29943070
Prostate cancer is one of the leading causes of cancer deaths, with no curative treatments once it spreads. Alternative therapies, including immunotherapy, have shown limited efficacy. Dendritic cells (DC) have...
6.
McDonagh P, Sundaresan G, Yang L, Sun M, Mikkelsen R, Zweit J
Nanomedicine . 2018 Apr; 14(4):1429-1440. PMID: 29641981
Cerium oxide nanoparticles (CONPs) have unique surface chemistry allowing catalyst-like antioxidant properties, and are being investigated for several disease indications in medicine. Studies have utilized surface modified CONPs toward this...
7.
Rabender C, Bruno N, Alam A, Sundaresan G, Zweit J, Mikkelsen R
J Pharmacol Exp Ther . 2018 Mar; 365(3):536-543. PMID: 29581154
Previously, we demonstrated that nitric oxide (NO) synthase (NOS) is uncoupled in a wide range of solid tumors and that restoring NOS coupling with the tetrahydrobiopterin precursor sepiapterin (SP) inhibits...
8.
Lamichhane N, Dewkar G, Sundaresan G, Wang L, Jose P, Otabashi M, et al.
J Nucl Med . 2017 Jul; 58(12):1997-2003. PMID: 28729428
Increasing evidence indicates that reduced intracellular drug accumulation is the parameter most consistently associated with platinum drug resistance, emphasizing the need to directly measure the intratumor drug concentration. In the...
9.
Lamichhane N, Dewkar G, Sundaresan G, Mahon R, Zweit J
Int J Mol Sci . 2017 May; 18(5). PMID: 28524076
Radiolabeled liposomes have been employed as diagnostic tools to monitor in vivo distribution of liposomes in real-time, which helps in optimizing the therapeutic efficacy of the liposomal drug delivery. This...
10.
Robertson C, Srivastava J, Siddiq A, Gredler R, Emdad L, Rajasekaran D, et al.
J Biol Chem . 2015 Jun; 290(29):18227-18236. PMID: 26070567
Astrocyte elevated gene-1 (AEG-1), also known as MTDH (metadherin) or LYRIC, is an established oncogene. However, the physiological function of AEG-1 is not known. To address this question, we generated...