Glenn Telling
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Explore the profile of Glenn Telling including associated specialties, affiliations and a list of published articles.
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22
Citations
358
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Recent Articles
1.
Benavente R, Brydon F, Bravo-Risi F, Soto P, Reed J, Lockwood M, et al.
Emerg Infect Dis
. 2025 Feb;
31(2):363-367.
PMID: 39983676
We describe chronic wasting disease (CWD) prion detection in raw and cooked meat from a CWD-positive elk. We found limited zoonotic potential in CWD prions from those meat products. Nonetheless,...
2.
Perez-Castro M, Perez-Castro M, Erana H, Vidal E, Charco J, Lorenzo N, et al.
PLoS Pathog
. 2025 Jan;
21(1):e1012890.
PMID: 39841704
Prion diseases, particularly sporadic cases, pose a challenge due to their complex nature and heterogeneity. The underlying mechanism of the spontaneous conversion from PrPC to PrPSc, the hallmark of prion...
3.
Soto P, Bravo-Risi F, Benavente R, Stimming T, Bodenchuk M, Whitley P, et al.
Emerg Infect Dis
. 2024 Dec;
31(1):168-173.
PMID: 39714396
Using a prion amplification assay, we identified prions in tissues from wild pigs (Sus scrofa) living in areas of the United States with variable chronic wasting disease (CWD) epidemiology. Our...
4.
Thackray A, McNulty E, Nalls A, Smith A, Comoy E, Telling G, et al.
J Biol Chem
. 2024 Aug;
300(9):107617.
PMID: 39089583
While animal prion diseases are a threat to human health, their zoonotic potential is generally inefficient because of interspecies prion transmission barriers. New animal models are required to provide an...
5.
Erana H, Sampedro-Torres-Quevedo C, Charco J, Diaz-Dominguez C, Peccati F, San-Juan-Ansoleaga M, et al.
Nat Commun
. 2024 Mar;
15(1):2112.
PMID: 38459071
Prion diseases are a group of rapidly progressing neurodegenerative disorders caused by the misfolding of the endogenous prion protein (PrP) into a pathogenic form (PrP). This process, despite being the...
6.
Thackray A, McNulty E, Nalls A, Cardova A, Tran L, Telling G, et al.
Biochem J
. 2023 Sep;
480(19):1485-1501.
PMID: 37747806
Chronic wasting disease is a fatal prion condition of cervids such as deer, elk, moose and reindeer. Secretion and excretion of prion infectivity from North American cervids with this condition...
7.
Vidal E, Sanchez-Martin M, Erana H, Perez Lazaro S, Perez-Castro M, Otero A, et al.
Acta Neuropathol Commun
. 2022 Dec;
10(1):179.
PMID: 36514160
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective...
8.
Mays C, Trinh T, Telling G, Kang H, Ryou C
Front Mol Neurosci
. 2022 Sep;
15:990136.
PMID: 36117913
Many questions surround the underlying mechanism for the differential metabolic processing observed for the prion protein (PrP) in healthy and prion-infected mammals. Foremost, the physiological α-cleavage of PrP interrupts a...
9.
Kramm C, Gomez-Gutierrez R, Soto C, Telling G, Nichols T, Morales R
PLoS One
. 2019 Dec;
14(12):e0226560.
PMID: 31887141
Chronic Wasting Disease (CWD) is a prion disease affecting several cervid species. Among them, white-tailed deer (WTD) are of relevance due to their value in farming and game hunting. The...
10.
Slapsak U, Salzano G, Ilc G, Giachin G, Bian J, Telling G, et al.
ACS Omega
. 2019 Dec;
4(22):19913-19924.
PMID: 31788624
Chronic wasting disease (CWD) is a highly infectious prion disease of cervids. Accumulation of prions, the disease-specific structural conformers of the cellular prion protein (PrP), in the central nervous system,...