Giulia Nizzoli
Overview
Explore the profile of Giulia Nizzoli including associated specialties, affiliations and a list of published articles.
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9
Citations
643
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Recent Articles
1.
Zagato E, Pozzi C, Bertocchi A, Schioppa T, Saccheri F, Guglietta S, et al.
Nat Microbiol
. 2020 Jan;
5(3):511-524.
PMID: 31988379
The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic effect has also been postulated. Here, we demonstrate that changes in the microbiota and mucus composition are...
2.
Burrello C, Garavaglia F, Cribiu F, Ercoli G, Lopez G, Troisi J, et al.
Nat Commun
. 2018 Dec;
9(1):5184.
PMID: 30518790
Alteration of the gut microbiota has been associated with different gastrointestinal disorders. Normobiosis restoration by faecal microbiota transplantation (FMT) is considered a promising therapeutic approach, even if the mechanisms underlying...
3.
Nizzoli G, Burrello C, Cribiu F, Lovati G, Ercoli G, Botti F, et al.
J Crohns Colitis
. 2018 Apr;
12(8):981-992.
PMID: 29697763
Background And Aims: T helper 17 [Th17] cells are crucially involved in the immunopathogenesis of inflammatory bowel diseases in humans. Nevertheless, pharmacological blockade of interleukin 17A [IL17A], the Th17 signature...
4.
Paroni M, Magarotto A, Tartari S, Nizzoli G, Larghi P, Ercoli G, et al.
Clin Transl Gastroenterol
. 2016 Jul;
7(7):e182.
PMID: 27415620
Objectives: To provide a functional and phenotypic characterization of immune cells infiltrating small intestinal mucosa during non-IPEX autoimmune enteropathy (AIE), as to gain insights on the pathogenesis of this clinical...
5.
Nizzoli G, Larghi P, Paroni M, Crosti M, Moro M, Neddermann P, et al.
Eur J Immunol
. 2016 May;
46(7):1622-32.
PMID: 27129615
IL-10 is an anti-inflammatory cytokine that inhibits maturation and cytokine production of dendritic cells (DCs). Although mature DCs have the unique capacity to prime CD8(+) CTL, IL-10 can promote CTL...
6.
Geginat J, Larghi P, Paroni M, Nizzoli G, Penatti A, Pagani M, et al.
Cytokine Growth Factor Rev
. 2016 Mar;
30:87-93.
PMID: 26980675
Interleukin-10 (IL-10) is known to be a tolerogenic cytokine since it inhibits pro-inflammatory cytokine production and T cell stimulatory capacities of myeloid cells, such as macrophages and dendritic cells. In...
7.
Geginat J, Nizzoli G, Paroni M, Maglie S, Larghi P, Pascolo S, et al.
Front Immunol
. 2015 Nov;
6:527.
PMID: 26528289
Dendritic cells (DCs) are specialized antigen-presenting cells (APCs) that have a key role in immune responses because they bridge the innate and adaptive arms of the immune system. They mature...
8.
Kastirr I, Maglie S, Paroni M, Alfen J, Nizzoli G, Sugliano E, et al.
J Immunol
. 2014 Aug;
193(7):3322-31.
PMID: 25172491
IL-21 promotes Th17 differentiation, and Th17 cells that upregulate T-bet, IFN-γ, and GM-CSF drive experimental autoimmune diseases in mice. Anti-IL-21 treatment of autoimmune patients is therefore a therapeutic option, but...
9.
Nizzoli G, Krietsch J, Weick A, Steinfelder S, Facciotti F, Gruarin P, et al.
Blood
. 2013 Jun;
122(6):932-42.
PMID: 23794066
Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice, CD8α(+)DC are specialized to cross-prime CD8(+) T cells and produce interleukin-12 (IL-12) that promotes cytotoxicity. Human...