Gisela Keller
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Explore the profile of Gisela Keller including associated specialties, affiliations and a list of published articles.
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78
Citations
1618
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Recent Articles
1.
Plum P, Monig S, Gockel I, Keller G, Ott K
Chirurgie (Heidelb)
. 2024 Aug;
95(9):685-695.
PMID: 39120691
Benign and malignant diseases of the upper gastrointestinal tract show gender-specific differences. The frequent gastroesophageal reflux disease is a prime example: men have an erosive reflux disease more often than...
2.
Grosser B, Heyer C, Austgen J, Sipos E, Reitsam N, Hauser A, et al.
Gastric Cancer
. 2023 Oct;
27(1):72-85.
PMID: 37874427
Background: Recently, we presented Stroma AReactive Invasion Front Areas (SARIFA) as a new histomorphologic negative prognostic biomarker in gastric cancer. It is defined as direct contact between tumor cells and...
3.
Kohlruss M, Chakraborty S, Hapfelmeier A, Jesinghaus M, Slotta-Huspenina J, Novotny A, et al.
J Cancer Res Clin Oncol
. 2023 Oct;
149(20):17727-17737.
PMID: 37819581
Purpose: We recently showed that low microsatellite instability (MSI-L) is associated with a good response to platinum/5-fluorouracil (5-FU) neoadjuvant chemotherapy (CTx) in gastric cancer. The purpose of this study was...
4.
Stogbauer F, Gess B, Brambs C, Lautizi M, Kacprowski T, Ourailidis I, et al.
Cancers (Basel)
. 2023 Aug;
15(15).
PMID: 37568650
The molecular characterization of endometrial endometrioid adenocarcinomas has provided major advances in its prognostic stratification. However, risk assessment of microsatellite instability (MSI) and copy-number (CN)-low cases remains a challenge. Thus,...
5.
Hess T, Maj C, Gehlen J, Borisov O, Haas S, Gockel I, et al.
EBioMedicine
. 2023 Jul;
94:104709.
PMID: 37480624
No abstract available.
6.
Griger J, Widholz S, Jesinghaus M, de Andrade Kratzig N, Lange S, Engleitner T, et al.
Cancer Cell
. 2023 Jun;
41(7):1327-1344.e10.
PMID: 37352862
Gastric neuroendocrine carcinomas (G-NEC) are aggressive malignancies with poorly understood biology and a lack of disease models. Here, we use genome sequencing to characterize the genomic landscapes of human G-NEC...
7.
Hess T, Maj C, Gehlen J, Borisov O, Haas S, Gockel I, et al.
EBioMedicine
. 2023 May;
92:104616.
PMID: 37209533
Background: Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopathology (diffuse/intestinal). We aimed to characterize the genetic risk architecture of GC according to its subtypes. Another aim...
8.
Hiltner T, Kohlruss M, Herz A, Lorenzen S, Novotny A, Hapfelmeier A, et al.
J Cancer Res Clin Oncol
. 2023 Mar;
149(10):7651-7662.
PMID: 37000259
Purpose: To investigate the prognostic role of microsatellite instability (MSI) in association with sex of patients treated with platinum/fluoropyrimidine neoadjuvant chemotherapy (CTx) with or without a taxane-containing compound. Methods: Of...
9.
Hiltner T, Szorenyi N, Kohlruss M, Hapfelmeier A, Herz A, Slotta-Huspenina J, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765729
We aimed to determine the clinical and prognostic relevance of allelic imbalance (AI) of the major histocompatibility complex (MHC) class I genes, encompassing the human leukocyte antigen (HLA) class I...
10.
Direct prediction of genetic aberrations from pathology images in gastric cancer with swarm learning
Saldanha O, Muti H, Grabsch H, Langer R, Dislich B, Kohlruss M, et al.
Gastric Cancer
. 2022 Oct;
26(2):264-274.
PMID: 36264524
Background: Computational pathology uses deep learning (DL) to extract biomarkers from routine pathology slides. Large multicentric datasets improve performance, but such datasets are scarce for gastric cancer. This limitation could...