Gisela A Kuhn
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Explore the profile of Gisela A Kuhn including associated specialties, affiliations and a list of published articles.
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33
Citations
756
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Recent Articles
1.
Mathavan N, Singh A, Marques F, Gunther D, Kuhn G, Wehrle E, et al.
Sci Adv
. 2025 Jan;
11(1):eadp8496.
PMID: 39742473
In recent decades, the field of bone mechanobiology has sought experimental techniques to unravel the molecular mechanisms governing the phenomenon of mechanically regulated fracture healing. Each cell within a fracture...
2.
Yilmaz D, Singh A, Wehrle E, Kuhn G, Mathavan N, Muller R
Front Aging
. 2024 Oct;
5:1365716.
PMID: 39372332
Frailty, a geriatric syndrome, is assessed using the frailty phenotype (FP) and frailty index (FI). While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse...
3.
Nayer B, Tan J, Alshoubaki Y, Lu Y, Legrand J, Lau S, et al.
Nat Commun
. 2024 Sep;
15(1):7863.
PMID: 39251592
Regulatory T cells (Tregs) are crucial immune cells for tissue repair and regeneration. However, their potential as a cell-based regenerative therapy is not yet fully understood. Here, we show that...
4.
Singh A, Yilmaz D, Wehrle E, Kuhn G, Muller R
FEBS Open Bio
. 2024 Jul;
14(10):1668-1681.
PMID: 39073017
Ageing is an inherent and intricate biological process that takes place in living organisms as time progresses. It involves the decline of multiple physiological functions, leading to body structure and...
5.
Yilmaz D, Marques F, Fischer Y, Zimmermann S, Hwang G, Atkins P, et al.
Heliyon
. 2024 Jul;
10(12):e32949.
PMID: 39021958
Osteoclasts are essential for bone remodeling by adapting their resorptive activity in response to their mechanical environment. However, the molecular mechanisms underlying this process remain unclear. Here, we demonstrated the...
6.
Yilmaz D, Mathavan N, Wehrle E, Kuhn G, Muller R
Ageing Res Rev
. 2023 Nov;
93:102118.
PMID: 37935249
Musculoskeletal aging encompasses the decline in bone and muscle function, leading to conditions such as frailty, osteoporosis, and sarcopenia. Unraveling the underlying molecular mechanisms and developing effective treatments are crucial...
7.
Lee S, Kleger N, Kuhn G, Greutert H, Du X, Smit T, et al.
Adv Mater
. 2023 Aug;
35(44):e2302008.
PMID: 37632210
Advances in additive manufacturing have led to diverse patient-specific implant designs utilizing computed tomography, but this requires intensive work and financial implications. Here, Digital Light Processing is used to fabricate...
8.
Boaretti D, Marques F, Ledoux C, Singh A, Kendall J, Wehrle E, et al.
Front Bioeng Biotechnol
. 2023 Mar;
11:1091294.
PMID: 36937760
Bone remodeling is regulated by the interaction between different cells and tissues across many spatial and temporal scales. Notably, models are regarded as powerful tools to further understand the signaling...
9.
Yang K, Goff E, Cheng K, Kuhn G, Wang Y, Cheng J, et al.
Bone
. 2022 Nov;
166:116594.
PMID: 36341948
Aim: Abnormal osteocyte lacunar morphology in adolescent idiopathic scoliosis (AIS) has been reported while the results were limited by the number of osteocyte lacunae being quantified. The present study aimed...
10.
Greve S, Kuhn G, Saenz-de-Juano M, Ghosh A, von Meyenn F, Giller K
Sci Rep
. 2022 Aug;
12(1):13161.
PMID: 35915220
Scientific evidence suggests that not only murine scent communication is regulated by major urinary proteins, but that their expression may also vary in response to metabolism via a yet unknown...