Giorgia Pallocca
Overview
Explore the profile of Giorgia Pallocca including associated specialties, affiliations and a list of published articles.
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23
Citations
331
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Recent Articles
1.
Marx U, Beken S, Chen Z, Dehne E, Doherty A, Ewart L, et al.
ALTEX
. 2025 Jan;
PMID: 39827406
The regular workshops held by the Center for Alternatives to Animal Testing (CAAT) on biology-inspired microphysiological systems (MPS) taking place every four years, have become a reliable measure to assess...
2.
Collen E, Bartmann K, Blum J, Carstens K, Celardo I, Chatterjee N, et al.
ALTEX
. 2025 Jan;
PMID: 39826153
On occasion of the DNT5 meeting in Konstanz, Germany (April-2024), participants brainstormed on future challenges concerning a regulatory implementation of the developmental neurotoxicity (DNT) in vitro test battery (DNT-IVB). The...
3.
Magel V, Blum J, Dolde X, Leisner H, Grillberger K, Khalidi H, et al.
Cells
. 2025 Jan;
13(24.
PMID: 39768149
Cell-based test methods with a phenotypic readout are frequently used for toxicity screening. However, guidance on how to validate the hits and how to integrate this information with other data...
4.
Tal T, Myhre O, Fritsche E, Ruegg J, Craenen K, Aiello-Holden K, et al.
Front Toxicol
. 2024 May;
6:1359507.
PMID: 38742231
In the European regulatory context, rodent studies are the predominant source of neurotoxicity information. Although they form a cornerstone of neurotoxicological assessments, they are costly and the topic of ethical...
5.
Holzer A, Dreser N, Pallocca G, Mangerich A, Stacey G, Dipalo M, et al.
ALTEX
. 2023 Oct;
40(4):706-712.
PMID: 37889190
Every test procedure, scientific and non-scientific, has inherent uncertainties, even when performed according to a standard operating procedure (SOP). In addition, it is prone to errors, defects, and mistakes introduced...
6.
Suciu I, Pamies D, Peruzzo R, Wirtz P, Smirnova L, Pallocca G, et al.
Arch Toxicol
. 2023 May;
97(7):2035-2049.
PMID: 37258688
To transfer toxicological findings from model systems, e.g. animals, to humans, standardized safety factors are applied to account for intra-species and inter-species variabilities. An alternative approach would be to measure...
7.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, Kock J, et al.
Altern Lab Anim
. 2022 Dec;
50(6):381-413.
PMID: 36458800
The adoption of on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and...
8.
Pallocca G, Leist M
ALTEX
. 2022 Jul;
39(3):531-539.
PMID: 35871507
In many countries, animal experiments can only be performed when their necessity has been demonstrated in a legal document. As the usefulness of animals in research is also a significant...
9.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, Kock J, et al.
Altern Lab Anim
. 2022 May;
50(2):90-120.
PMID: 35578444
Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction and Refinement of...
10.
Pallocca G, Rovida C, Leist M
ALTEX
. 2022 Apr;
39(2):347-353.
PMID: 35413127
Banning or reduction of the use of animals for laboratory experiments is a frequently-discussed societal and scientific issue. Moreover, the usefulness of animals needs to be considered in any decision...