Giorgia Pallocca
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Explore the profile of Giorgia Pallocca including associated specialties, affiliations and a list of published articles.
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23
Citations
331
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Recent Articles
11.
Pallocca G, Mone M, Kamp H, Luijten M, van de Water B, Leist M
ALTEX
. 2022 Apr;
39(3):419–426.
PMID: 35404467
In many industrial sectors, there is a need for reliable ways to evaluate the safety of chemicals with methods anchored to human biology and pathology. For this purpose, many animal-free...
12.
Krebs A, van Vugt-Lussenburg B, Waldmann T, Albrecht W, Boei J, Ter Braak B, et al.
Arch Toxicol
. 2020 Jul;
94(7):2435-2461.
PMID: 32632539
Hazard assessment, based on new approach methods (NAM), requires the use of batteries of assays, where individual tests may be contributed by different laboratories. A unified strategy for such collaborative...
13.
Busquet F, Hartung T, Pallocca G, Rovida C, Leist M
Arch Toxicol
. 2020 May;
94(6):2263-2272.
PMID: 32447523
The COVID-19-inducing virus, SARS-CoV2, is likely to remain a threat to human health unless efficient drugs or vaccines become available. Given the extent of the current pandemic (people in over...
14.
Rovida C, Barton-Maclaren T, Benfenati E, Caloni F, Chandrasekera P, Chesne C, et al.
ALTEX
. 2020 May;
37(4):579-606.
PMID: 32369604
Read-across (RAx) translates available information from well-characterized chemicals to a substance for which there is a toxicological data gap. The OECD is working on case studies to probe general applicability...
15.
Marx U, Akabane T, Andersson T, Baker E, Beilmann M, Beken S, et al.
ALTEX
. 2020 Mar;
37(3):365-394.
PMID: 32113184
The first microfluidic microphysiological systems (MPS) entered the academic scene more than 15 years ago and were considered an enabling technology to human (patho)biology in vitro and, therefore, provide alternative...
16.
Krebs A, Waldmann T, Wilks M, van Vugt-Lussenburg B, van der Burg B, Terron A, et al.
ALTEX
. 2020 Jan;
37(1):164.
PMID: 31960940
In this manuscript, which appeared in ALTEX (2019), 36(4), 682- 699, doi:10.14573/altex.1909271 , the affiliation of Hennicke Kamp should be Experimental Toxicology and Ecology, BASF SE, Ludwigshafen, Germany. Further, the...
17.
Krebs A, Nyffeler J, Karreman C, Schmidt B, Kappenberg F, Mellert J, et al.
ALTEX
. 2019 Dec;
37(1):155-163.
PMID: 31833558
Many toxicological test methods, including assays of cell viability and function, require an evaluation of concentration-response data. This often involves curve fitting, and the resulting mathematical functions are then used...
18.
Krebs A, Waldmann T, Wilks M, van Vugt-Lussenburg B, van der Burg B, Terron A, et al.
ALTEX
. 2019 Oct;
36(4):682-699.
PMID: 31658359
Only few cell-based test methods are described by Organisation for Economic Co-operation and Development (OECD) test guidelines or other regulatory references (e.g., the European Pharmacopoeia). The majority of toxicity tests...
19.
20.
Pallocca G, Nyffeler J, Dolde X, Grinberg M, Gstraunthaler G, Waldmann T, et al.
Arch Toxicol
. 2017 Apr;
91(10):3385-3402.
PMID: 28365849
Human cell-based toxicological assays have been used successfully to detect known toxicants, and to distinguish them from negative controls. However, there is at present little experience on how to deal...