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Gilles Laverny

Explore the profile of Gilles Laverny including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1008
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Recent Articles
1.
Giannini M, Rovito D, Oulad-Abdelghani M, Messaddeq N, Debrut L, Quiring G, et al.
RMD Open . 2025 Mar; 11(1). PMID: 40044571
Introduction: Inflammatory myopathies (IM) are a group of severe autoimmune diseases, sharing some similarities, whose cause is unknown and treatment is empirical.While C-protein-induced myositis (CIM), the most currently used mouse...
2.
Len-Tayon K, Metzger D, Laverny G
Med Sci (Paris) . 2025 Mar; 41(2):154-159. PMID: 40028953
Prostate cancer is the third leading cause of cancer-related death among men in developed countries. Hormone and chemotherapy are the standard of care for advanced prostate cancer, but most patients...
3.
Yanushko D, German Falcon B, El Bizri R, Pervizou D, Dolgos R, Keime C, et al.
Cell Death Dis . 2025 Jan; 16(1):46. PMID: 39865080
Prostate cancer is a heterogeneous disease with a slow progression and a highly variable clinical outcome. The tumor suppressor genes PTEN and TP53 are frequently mutated in prostate cancer and...
4.
Len-Tayon K, Beraud C, Fauveau C, Belorusova A, Chebaro Y, Mourino A, et al.
Br J Pharmacol . 2024 Jul; 181(21):4279-4293. PMID: 38982588
Background And Purpose: Castration-resistant prostate cancer (CRPC) is a common male malignancy that requires new therapeutic strategies due to acquired resistance to its first-line treatment, docetaxel. The benefits of vitamin...
5.
Peluso-Iltis C, Pierrat N, Rovito D, Osz J, Sawada D, Kittaka A, et al.
Biomolecules . 2024 May; 14(5). PMID: 38785958
The active vitamin D metabolites, 25-hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D), are produced by successive hydroxylation steps and play key roles in several cellular processes. However, alternative metabolic pathways...
6.
Cai Q, Sahu R, Ueberschlag-Pitiot V, Souali-Crespo S, Charvet C, Silem I, et al.
Nat Commun . 2024 Apr; 15(1):3563. PMID: 38670969
Synthetic glucocorticoids (GC), such as dexamethasone, are extensively used to treat chronic inflammation and autoimmune disorders. However, long-term treatments are limited by various side effects, including muscle atrophy. GC activities...
7.
Paradis S, Charles A, Giannini M, Meyer A, Lejay A, Talha S, et al.
Int J Mol Sci . 2024 Apr; 25(7). PMID: 38612835
Peripheral arterial disease (PAD) strikes more than 200 million people worldwide and has a severe prognosis by potentially leading to limb amputation and/or death, particularly in older patients. Skeletal muscle...
8.
Giannini M, Charles A, Evrard C, Blaess J, Bouchard-Marmen M, Debrut L, et al.
Rheumatology (Oxford) . 2024 Mar; 63(9):2503-2514. PMID: 38544289
Objectives: To assess the ability of dual-energy X-ray absorptiometry (DXA) and hand-grip dynamometer to measure damage in inflammatory myopathies (IM). Methods: Forty adult IM patients with a disease duration ≥12 ...
9.
Zaloszyc A, Bernardor J, Bacchetta J, Laverny G, Peter Schmitt C
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982400
Patients with chronic kidney disease (CKD) inevitably develop mineral and bone disorders (CKD-MBD), which negatively impact their survival and quality of life. For a better understanding of underlying pathophysiology and...
10.
Belorusova A, Rovito D, Chebaro Y, Doms S, Verlinden L, Verstuyf A, et al.
Int J Mol Sci . 2022 Aug; 23(15). PMID: 35955580
The Vitamin D receptor (VDR) plays a key role in calcium homeostasis, as well as in cell proliferation and differentiation. Among the large number of VDR ligands that have been...