Gilberto S Almeida
Overview
Explore the profile of Gilberto S Almeida including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
194
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0
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Recent Articles
1.
King D, Li X, Almeida G, Kwok C, Gravells P, Harrison D, et al.
Oncotarget
. 2023 Jan;
14:21-22.
PMID: 36634205
No abstract available.
2.
Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, et al.
J Clin Invest
. 2020 Oct;
130(11):5875-5892.
PMID: 33016930
The undruggable nature of oncogenic Myc transcription factors poses a therapeutic challenge in neuroblastoma, a pediatric cancer in which MYCN amplification is strongly associated with unfavorable outcome. Here, we show...
3.
King D, Li X, Almeida G, Kwok C, Gravells P, Harrison D, et al.
Oncotarget
. 2020 Jun;
11(23):2141-2159.
PMID: 32577161
This study investigates the influence expression of the MYCN oncogene has on the DNA damage response, replication fork progression and sensitivity to PARP inhibition in neuroblastoma. In a panel of...
4.
Yogev O, Almeida G, Barker K, George S, Kwok C, Campbell J, et al.
Cancer Res
. 2019 Aug;
79(20):5382-5393.
PMID: 31405846
Neuroblastoma is a pediatric cancer that is frequently metastatic and resistant to conventional treatment. In part, a lack of natively metastatic, chemoresistant models has limited our insight into the development...
5.
Papaevangelou E, Almeida G, Box C, deSouza N, Chung Y
Int J Cancer
. 2018 Mar;
143(4):992-1002.
PMID: 29569717
Overexpression of fatty acid synthase (FASN), a key regulator of the de novo synthesis of fatty acids, has been demonstrated in a variety of cancers and is associated with poor...
6.
Almeida G, Panek R, Hallsworth A, Webber H, Papaevangelou E, Boult J, et al.
Br J Cancer
. 2017 Aug;
117(6):791-800.
PMID: 28787429
Background: The use of clinical MRI scanners to conduct pre-clinical research facilitates comparisons with clinical studies. Here the utility and sensitivity of anatomical and functional MRI data/biomarkers acquired from transgenic...
7.
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS
Almeida G, Bawn C, Galler M, Wilson I, Thomas H, Kyle S, et al.
NMR Biomed
. 2017 May;
30(9).
PMID: 28543772
Poly(adenosine diphosphate ribose) polymerases (PARPs) are multifunctional proteins which play a role in many cellular processes. Namely, PARP1 and PARP2 have been shown to be involved in DNA repair, and...
8.
Yogev O, Barker K, Sikka A, Almeida G, Hallsworth A, Smith L, et al.
Cancer Res
. 2016 May;
76(10):3025-35.
PMID: 27197232
Neuroblastoma is the most common childhood extracranial solid tumor. In high-risk cases, many of which are characterized by amplification of MYCN, outcome remains poor. Mutations in the p53 (TP53) tumor...
9.
Doblas S, Almeida G, Ble F, Garteiser P, Hoff B, McIntyre D, et al.
J Magn Reson Imaging
. 2015 May;
42(6):1759-64.
PMID: 26012876
Purpose: To evaluate between-site agreement of apparent diffusion coefficient (ADC) measurements in preclinical magnetic resonance imaging (MRI) systems. Materials And Methods: A miniaturized thermally stable ice-water phantom was devised. ADC...
10.
Vormoor B, Knizia H, Batey M, Almeida G, Wilson I, Dildey P, et al.
PLoS One
. 2014 Jan;
9(1):e85128.
PMID: 24409320
Ewing sarcoma and osteosarcoma represent the two most common primary bone tumours in childhood and adolescence, with bone metastases being the most adverse prognostic factor. In prostate cancer, osseous metastasis...