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Gilbert N Lam

Explore the profile of Gilbert N Lam including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 68
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Recent Articles
1.
Bonate P, Cunningham C, Gaynon P, Jeha S, Kadota R, Lam G, et al.
Cancer Chemother Pharmacol . 2010 Jun; 67(4):875-90. PMID: 20582417
Clofarabine for injection is a second-generation nucleoside analog approved in the United States (Clolar(®)) and Europe (Evoltra(®)) for the treatment of pediatric relapsed or refractory acute lymphoblastic leukemia. This report...
2.
Beer T, Javle M, Ryan C, Garzotto M, Lam G, Wong A, et al.
Cancer Chemother Pharmacol . 2006 Oct; 59(5):581-7. PMID: 17066293
Background: DN-101 is a new, high-dose, oral formulation of calcitriol under investigation for the treatment of cancer. We sought to evaluate the tolerability and pharmacokinetics (PK) of weekly doses of...
3.
Beer T, Javle M, Lam G, Henner W, Wong A, Trump D
Clin Cancer Res . 2005 Nov; 11(21):7794-9. PMID: 16278401
Background: Intermittent administration allows substantial dose escalation of calcitriol but limited bioavailability of the commercially available formulations at high doses is limiting. In this dose escalation study, we sought to...
4.
Bonate P, Craig A, Gaynon P, Gandhi V, Jeha S, Kadota R, et al.
J Clin Pharmacol . 2004 Oct; 44(11):1309-22. PMID: 15496649
The population pharmacokinetics of plasma clofarabine and intracellular clofarabine triphosphate were characterized in pediatric patients with acute leukemias. Traditional model-building techniques with NONMEM were used. Covariates were entered into the...