Gila Kazimirsky
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Explore the profile of Gila Kazimirsky including associated specialties, affiliations and a list of published articles.
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24
Citations
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Recent Articles
11.
Betzer O, Shwartz A, Motiei M, Kazimirsky G, Gispan I, Damti E, et al.
ACS Nano
. 2014 Aug;
8(9):9274-85.
PMID: 25133802
A critical problem in the development and implementation of stem cell-based therapy is the lack of reliable, noninvasive means to image and trace the cells post-transplantation and evaluate their biodistribution,...
12.
Perlstein B, Finniss S, Miller C, Okhrimenko H, Kazimirsky G, Cazacu S, et al.
Neuro Oncol
. 2012 Nov;
15(1):29-40.
PMID: 23144078
Glioblastomas (GBM) are characterized by resistance to chemotherapy and radiotherapy, and therefore, alternative therapeutic approaches are needed. TRAIL induces apoptosis in cancer but not in normal cells and is considered...
13.
Ziv-Av A, Taller D, Attia M, Xiang C, Lee H, Cazacu S, et al.
Cell Signal
. 2011 Jul;
23(12):1936-43.
PMID: 21777672
Gliomas are characterized by increased infiltration into the surrounding normal brain tissue. We recently reported that RTVP-1 is highly expressed in gliomas and plays a role in the migration of...
14.
Lee H, Xiang C, Cazacu S, Finniss S, Kazimirsky G, Lemke N, et al.
Neuro Oncol
. 2008 Apr;
10(3):236-43.
PMID: 18403493
We characterized the expression and function of the endoplasmic reticulum protein GRP78 in glial tumors. GRP78 is highly expressed in glioblastomas but not in oligodendrogliomas, and its expression is inversely...
15.
Steinhart R, Kazimirsky G, Okhrimenko H, Ben-Hur T, Brodie C
Glia
. 2006 Nov;
55(2):224-32.
PMID: 17091491
In this study, we examined the role of PKC in the differentiation of multipotential neural precursor cells (NPCs). We found that the NPCs expressed PKCalpha,beta2,delta,epsilon,zeta and low levels of PKCgamma....
16.
Rosenzweig T, Ziv-Av A, Xiang C, Lu W, Cazacu S, Taler D, et al.
Cancer Res
. 2006 Apr;
66(8):4139-48.
PMID: 16618735
In this study, we examined the expression and functions of related to testes-specific, vespid, and pathogenesis protein 1 (RTVP-1) in glioma cells. RTVP-1 was expressed in high levels in glioblastomas,...
17.
Okhrimenko H, Lu W, Xiang C, Hamburger N, Kazimirsky G, Brodie C
Cancer Res
. 2005 Aug;
65(16):7301-9.
PMID: 16103081
In this study, we examined the role of protein kinase C (PKC)-epsilon in the apoptosis and survival of glioma cells using tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-stimulated cells and...
18.
Okhrimenko H, Lu W, Xiang C, Ju D, Blumberg P, Gomel R, et al.
J Biol Chem
. 2005 Mar;
280(25):23643-52.
PMID: 15774464
Protein kinase Cdelta (PKCdelta) regulates cell apoptosis in a cell- and stimulus-specific manner. Here, we studied the role of PKCdelta in the apoptotic effect of TRAIL in glioma cells. We...
19.
Deutsch E, Cohen A, Kazimirsky G, Dovrat S, Rubinfeld H, Brodie C, et al.
J Virol
. 2004 Aug;
78(18):10187-92.
PMID: 15331751
TPA (12-O-tetradecanoylphorbol-13-acetate), a well-known activator of protein kinase C (PKC), can experimentally induce reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) in certain latently infected cells. We selectively blocked the activity of...
20.
Brodie C, Steinhart R, Kazimirsky G, Rubinfeld H, Hyman T, Ayres J, et al.
Mol Pharmacol
. 2004 Jun;
66(1):76-84.
PMID: 15213298
RasGRP is a family of guanine nucleotide exchange factors that activate small GTPases and contain a C1 domain similar to the one present in protein kinase C (PKC). In this...