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Gijs van Son

Explore the profile of Gijs van Son including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 235
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Recent Articles
1.
Geurts M, Gandhi S, Boretto M, Akkerman N, Derks L, van Son G, et al.
Nat Commun . 2023 Aug; 14(1):4998. PMID: 37591832
Optimization of CRISPR/Cas9-mediated genome engineering has resulted in base editors that hold promise for mutation repair and disease modeling. Here, we demonstrate the application of base editors for the generation...
2.
Boonekamp K, Heo I, Artegiani B, Asra P, van Son G, de Ligt J, et al.
Dev Biol . 2021 Feb; 474:37-47. PMID: 33571486
Canonical Wnt signaling plays a key role during organ development, homeostasis and regeneration and these processes are conserved between invertebrates and vertebrates. Mutations in Wnt pathway components are commonly found...
3.
Demmers L, Kretzschmar K, Van Hoeck A, Bar-Epraim Y, van den Toorn H, Koomen M, et al.
Nat Commun . 2020 Oct; 11(1):5338. PMID: 33087703
Tumor heterogeneity is a major cause of therapeutic resistance. Immunotherapy may exploit alternative vulnerabilities of drug-resistant cells, where tumor-specific human leukocyte antigen (HLA) peptide ligands are promising leads to invoke...
4.
Giobbe G, Crowley C, Luni C, Campinoti S, Khedr M, Kretzschmar K, et al.
Nat Commun . 2019 Dec; 10(1):5658. PMID: 31827102
Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is greatly limited by the lack of effective GMP-compliant systems for...