Gianfranca Corna
Overview
Explore the profile of Gianfranca Corna including associated specialties, affiliations and a list of published articles.
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16
Citations
580
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Recent Articles
1.
Raccosta L, Marinozzi M, Costantini S, Maggioni D, Ferreira L, Corna G, et al.
Cell Death Dis
. 2023 Feb;
14(2):129.
PMID: 36792589
Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic...
2.
Moresco M, Raccosta L, Corna G, Maggioni D, Soncini M, Bicciato S, et al.
Front Immunol
. 2018 Oct;
9:2251.
PMID: 30333826
Recent evidence indicates that immune cells contribute to the formation of tumor metastases by regulating the pre-metastatic niche. Whether tumor-derived factors involved in primary tumor formation play a role in...
3.
Vezzoli M, Sciorati C, Campana L, Monno A, Doglio M, Rigamonti E, et al.
Mol Med
. 2016 Dec;
22:809-820.
PMID: 27900389
Objective: The signals causing the resolution of muscle inflammation are only partially characterized. The long pentraxin PTX3, which modulates leukocyte recruitment and activation, could contribute. Methods: We analysed the expression...
4.
Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, et al.
Proc Natl Acad Sci U S A
. 2016 Sep;
113(41):E6219-E6227.
PMID: 27671648
Cells in the tumor microenvironment may be reprogrammed by tumor-derived metabolites. Cholesterol-oxidized products, namely oxysterols, have been shown to favor tumor growth directly by promoting tumor cell growth and indirectly...
5.
Lanterna C, Musumeci A, Raccosta L, Corna G, Moresco M, Maggioni D, et al.
Cancer Immunol Immunother
. 2016 Aug;
65(11):1303-1315.
PMID: 27520505
Tumor-derived metabolites dampen tumor-infiltrating immune cells and antitumor immune responses. Among the various metabolites produced by tumors, we recently showed that cholesterol oxidized products, namely oxysterols, favor tumor growth through...
6.
Corna G, Caserta I, Monno A, Apostoli P, Manfredi A, Camaschella C, et al.
J Immunol
. 2016 Jul;
197(5):1914-25.
PMID: 27465531
Macrophages recruited at the site of sterile muscle damage play an essential role in the regeneration of the tissue. In this article, we report that the selective disruption of macrophage...
7.
Raccosta L, Fontana R, Corna G, Maggioni D, Moresco M, Russo V
Cancer Immunol Immunother
. 2015 Dec;
65(1):111-7.
PMID: 26646851
Targeting the tumor microenvironment focusing on immune cells has recently become a standard of care for some tumors. Indeed, antibodies blocking immune checkpoints (e.g., anti-CTLA-4 and anti-PD1 mAbs) have been...
8.
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al.
PLoS One
. 2015 Jun;
10(6):e0128094.
PMID: 26039259
Muscle injury induces a classical inflammatory response in which cells of the innate immune system rapidly invade the tissue. Macrophages are prominently involved in this response and required for proper...
9.
Transplanted mesoangioblasts require macrophage IL-10 for survival in a mouse model of muscle injury
Bosurgi L, Corna G, Vezzoli M, Touvier T, Cossu G, Manfredi A, et al.
J Immunol
. 2012 May;
188(12):6267-77.
PMID: 22573810
The aim of this study was to verify whether macrophages influence the fate of transplanted mesoangioblasts--vessel-associated myogenic precursors--in a model of sterile toxin-induced skeletal muscle injury. We have observed that...
10.
Pagani A, Nai A, Corna G, Bosurgi L, Rovere-Querini P, Camaschella C, et al.
Blood
. 2011 Jun;
118(3):736-46.
PMID: 21628413
Hepcidin is an antimicrobial peptide that controls systemic iron homeostasis. Hepcidin binding to its receptor ferroportin reduces iron availability, thus controlling microbial growth. In parallel it triggers an anti-inflammatory response...