Ghislaine Guillemain
Overview
Explore the profile of Ghislaine Guillemain including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
266
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Recent Articles
1.
Guillemain G, Khemtemourian L, Brehat J, Morin D, Movassat J, Tourrel-Cuzin C, et al.
Biochimie
. 2024 Jun;
224:104-113.
PMID: 38908539
Amyloidosis forms a large family of pathologies associated with amyloid deposit generated by the formation of amyloid fibrils or plaques. The amyloidogenic proteins and peptides involved in these processes are...
2.
Komatsu J, Cico A, Poncin R, Le Bohec M, Morf J, Lipin S, et al.
Sci Rep
. 2023 Mar;
13(1):4866.
PMID: 36964177
Progress in sample preparation for scRNA-seq is reported based on RevGel-seq, a reversible-hydrogel technology optimized for samples of fresh cells. Complexes of one cell paired with one barcoded bead are...
3.
Guillemain G, Lacapere J, Khemtemourian L
Biochim Biophys Acta Biomembr
. 2022 Jul;
1864(10):184002.
PMID: 35868406
Loss of pancreatic β-cell mass is deleterious for type 2 diabetes patients since it reduces insulin production, critical for glucose homeostasis. The main research axis developed over the last few...
4.
Beaupere C, Liboz A, Feve B, Blondeau B, Guillemain G
Int J Mol Sci
. 2021 Jan;
22(2).
PMID: 33435513
Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism. These hormones are involved in tissue repair,...
5.
Salazar Vazquez S, Blondeau B, Cattan P, Armanet M, Guillemain G, Khemtemourian L
Biochimie
. 2019 Dec;
170:26-35.
PMID: 31838129
Type 2 diabetes mellitus is a disease characterized by the formation of amyloid fibrillar deposits consisting mainly in human islet amyloid polypeptide (hIAPP), a peptide co-produced and co-secreted with insulin....
6.
Courty E, Besseiche A, Do T, Liboz A, Aguid F, Quilichini E, et al.
Diabetes
. 2018 Oct;
68(1):95-108.
PMID: 30327384
Both type 1 and type 2 diabetes are characterized by deficient insulin secretion and decreased β-cell mass. Thus, regenerative strategies to increase β-cell mass need to be developed. To characterize...
7.
Khemtemourian L, Guillemain G, Foufelle F, Killian J
Biochimie
. 2017 Aug;
142:22-30.
PMID: 28778718
Type 2 diabetes mellitus is characterized histopathologically by the presence of fibrillary amyloid deposits in the pancreatic islets of Langerhans. Human islet amyloid polypeptide (hIAPP), the 37-residue pancreatic hormone, is...
8.
Ebou M, Singh-Estivalet A, Launay J, Callebert J, Tronche F, Ferre P, et al.
PLoS One
. 2016 May;
11(5):e0155174.
PMID: 27144400
[This corrects the article DOI: 10.1371/journal.pone.0149343.].
9.
Ebou M, Singh-Estivalet A, Launay J, Callebert J, Tronche F, Ferre P, et al.
PLoS One
. 2016 Feb;
11(2):e0149343.
PMID: 26901633
Diabetes is a major complication of chronic Glucocorticoids (GCs) treatment. GCs induce insulin resistance and also inhibit insulin secretion from pancreatic beta cells. Yet, a full understanding of this negative...
10.
Baraille F, Ayari S, Carriere V, Osinski C, Garbin K, Blondeau B, et al.
Diabetes
. 2015 Apr;
64(8):2744-56.
PMID: 25829452
Intestine contributes to energy homeostasis through the absorption, metabolism, and transfer of nutrients to the organism. We demonstrated previously that hepatocyte nuclear receptor-4α (HNF-4α) controls intestinal epithelium homeostasis and intestinal...