Ghim Siong Ow
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Explore the profile of Ghim Siong Ow including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
324
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Recent Articles
1.
Giannakakis A, Tsifintaris M, Gouzouasis V, Ow G, Aau M, Papp C, et al.
Front Oncol
. 2024 May;
14:1227151.
PMID: 38756663
Stress-induced promoter-associated and antisense lncRNAs (si-paancRNAs) originate from a reservoir of oxidative stress (OS)-specific promoters via RNAPII pausing-mediated divergent antisense transcription. Several studies have shown that the KDM7A divergent transcript...
2.
Papp C, Mukundan V, Jenjaroenpun P, Winnerdy F, Ow G, Phan A, et al.
Nucleic Acids Res
. 2023 Apr;
51(9):4148-4177.
PMID: 37094040
DNA sequence composition determines the topology and stability of G-quadruplexes (G4s). Bulged G-quadruplex structures (G4-Bs) are a subset of G4s characterized by 3D conformations with bulges. Current search algorithms fail...
3.
Duszka K, Ellero-Simatos S, Ow G, Defernez M, Paramalingam E, Tett A, et al.
Sci Rep
. 2018 Jul;
8(1):11338.
PMID: 30054525
The intestine is key for nutrient absorption and for interactions between the microbiota and its host. Therefore, the intestinal response to caloric restriction (CR) is thought to be more complex...
4.
Sundaram G, Ismail H, Bashir M, Muhuri M, Vaz C, Nama S, et al.
J Exp Med
. 2017 Aug;
214(10):2889-2900.
PMID: 28827448
Epithelial carcinomas are well known to activate a prolonged wound-healing program that promotes malignant transformation. Wound closure requires the activation of keratinocyte migration via a dual-state molecular switch. This switch...
5.
Chen L, Jenjaroenpun P, Pillai A, Ivshina A, Ow G, Efthimios M, et al.
Proc Natl Acad Sci U S A
. 2017 Mar;
114(11):E2215-E2224.
PMID: 28251929
Robust prognostic gene signatures and therapeutic targets are difficult to derive from expression profiling because of the significant heterogeneity within breast cancer (BC) subtypes. Here, we performed forward genetic screening...
6.
Ow G, Kuznetsov V
Sci Rep
. 2016 Nov;
6:36493.
PMID: 27819294
The field of personalized and precise medicine in the era of big data analytics is growing rapidly. Previously, we proposed our model of patient classification termed Prognostic Signature Vector Matching...
7.
Ow G, Tang Z, Kuznetsov V
Oncotarget
. 2016 May;
7(26):40200-40220.
PMID: 27229533
The era of big data and precision medicine has led to accumulation of massive datasets of gene expression data and clinical information of patients. For a new patient, we propose...
8.
Grinchuk O, Motakis E, Yenamandra S, Ow G, Jenjaroenpun P, Tang Z, et al.
Oncotarget
. 2015 Oct;
6(39):42197-221.
PMID: 26517092
More than 30% of human protein-coding genes form hereditary complex genome architectures composed of sense-antisense (SA) gene pairs (SAGPs) transcribing their RNAs from both strands of a given locus. Such...
9.
Aswad L, Yenamandra S, Ow G, Grinchuk O, Ivshina A, Kuznetsov V
Oncotarget
. 2015 Oct;
6(34):36652-74.
PMID: 26474389
Invasive ductal carcinoma (IDC) is a major histo-morphologic type of breast cancer. Histological grading (HG) of IDC is widely adopted by oncologists as a prognostic factor. However, HG evaluation is...
10.
Goh W, Ow G, Kuznetsov V, Chong S, Lim Y
Am J Transl Res
. 2015 Aug;
7(6):1140-51.
PMID: 26279757
An iTRAQ-based tandem mass spectrometry approach was employed to relatively quantify proteins in the membrane proteome of eleven gastric cancer cell lines relative to a denominator non-cancer gastric epithelial cell...