Gethin R Owen
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Explore the profile of Gethin R Owen including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
136
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Recent Articles
1.
Salmond N, Khanna K, Owen G, Williams K
Nanoscale
. 2021 Jan;
13(3):2012-2025.
PMID: 33449064
Extracellular vesicles (EVs) are lipid membrane enclosed nano-sized structures released into the extracellular environment by all cell types. EV constituents include proteins, lipids and nucleic acids that reflect the cell...
2.
Bi J, Koivisto L, Pang A, Li M, Jiang G, Aurora S, et al.
Sci Rep
. 2017 Jul;
7(1):4411.
PMID: 28667248
Periodontal diseases manifest by the formation of deep pockets between the gingiva and teeth where multispecies bacterial biofilms flourish, causing inflammation and bone loss. Epithelial cell receptor αvβ6 integrin that...
3.
Huang P, Bi J, Owen G, Chen W, Rokka A, Koivisto L, et al.
J Invest Dermatol
. 2015 Aug;
135(12):3051-3059.
PMID: 26288358
Extracellular vesicles released from cells regulate many normal and pathological conditions. Little is known about the role of epidermal keratinocyte microvesicles (KC-MVs) in epithelial-stromal interaction that is essential for wound...
4.
Ferre F, Larjava H, Loison-Robert L, Berbar T, Owen G, Berdal A, et al.
Stem Cells Dev
. 2014 Jul;
23(23):2895-907.
PMID: 25003637
Human gingival stem cells (HGSCs) can be easily isolated and manipulated in culture to investigate their multipotency. Osteogenic differentiation of bone-marrow-derived mesenchymal stem/stromal cells has been well documented. HGSCs derive...
5.
Mohazab L, Koivisto L, Jiang G, Kytomaki L, Haapasalo M, Owen G, et al.
J Cell Sci
. 2012 Dec;
126(Pt 3):732-44.
PMID: 23264742
Tooth enamel has the highest degree of biomineralization of all vertebrate hard tissues. During the secretory stage of enamel formation, ameloblasts deposit an extracellular matrix that is in direct contact...
6.
Nylund C, Rappu P, Pakula E, Heino A, Laato L, Elo L, et al.
PLoS One
. 2012 Oct;
7(9):e45382.
PMID: 23028975
Cancer-testis (CT) antigens are predominantly expressed in testis or placenta, but absent in most adult tissues. During malignant transformation CT genes are often activated. CT antigen 16 (CT16, PAGE5) is...
7.
Xie Y, McElwee K, Owen G, Hakkinen L, Larjava H
J Invest Dermatol
. 2011 Nov;
132(3 Pt 1):547-55.
PMID: 22113470
Integrin αvβ6 is an epithelial-specific receptor that binds and activates latent transforming growth factor-β1 (TGF-β1). TGF-β1 has been implicated as an endogenous inducer of hair follicle (HF) regression during hair...
8.
Owen G, Stokes D
Dermatol Res Pract
. 2010 Jul;
2010:930401.
PMID: 20672011
Desmosomes are a complex assembly of protein molecules that mediate adhesion between adjacent cells. Desmosome composition is well established and spatial relationships between components have been identified. Intercellular cell-cell adhesion...
9.
Petricca G, Leppilampi M, Jiang G, Owen G, Wiebe C, Tu Y, et al.
Eur J Oral Sci
. 2009 Sep;
117(5):518-27.
PMID: 19758247
Kindlin-1 is an intracellular focal adhesion protein that regulates the actin cytoskeleton. Patients suffering from Kindler syndrome have a homologous mutation of the kindlin-1 gene and develop skin blisters, periodontal...