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Gesine Flehmig

Explore the profile of Gesine Flehmig including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 361
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Recent Articles
1.
Lehmann S, Retschlag U, Oberbach A, Morgenroth R, Linder N, Schaudinn A, et al.
Diabetes Obes Metab . 2024 Jul; 26(9):4087-4099. PMID: 39014526
Aim: To compare the effectiveness of strength versus endurance training on reducing visceral fat in individuals with obesity. Materials And Methods: For the STrength versus ENdurance (STEN) 24-month randomized clinical...
2.
Fritsche L, Loffler D, Kantartzis K, Flehmig G, Roden M, Fritsche A, et al.
J Clin Endocrinol Metab . 2024 Mar; 109(10):2571-2578. PMID: 38487818
Context: Breastfeeding is associated with a reduced maternal risk for cardiovascular diseases (CVDs). Objective: Since the underlying mechanisms are still poorly understood, we here examined the effect of breastfeeding on...
3.
Hoffmann A, Ebert T, Hankir M, Flehmig G, Kloting N, Jessnitzer B, et al.
Nutrients . 2021 Aug; 13(8). PMID: 34444659
Lipodystrophy syndromes (LD) are a heterogeneous group of very rare congenital or acquired disorders characterized by a generalized or partial lack of adipose tissue. They are strongly associated with severe...
4.
Kunath A, Heiker J, Kern M, Kosacka J, Flehmig G, Stumvoll M, et al.
Horm Metab Res . 2020 Jul; 52(12):877-881. PMID: 32629517
The C57BL/6J (B6J) mouse strain has been widely used as a control strain for the study of metabolic diseases and diet induced obesity (DIO). B6J mice carry a spontaneous deletion...
5.
Langhardt J, Flehmig G, Kloting N, Lehmann S, Ebert T, Kern M, et al.
Obes Facts . 2018 Dec; 11(6):475-490. PMID: 30537708
Background/aims: Altered expression and circulating levels of glutathione peroxidase 3 (GPX3) have been observed in obesity and type 2 diabetes (T2D) across species. Here, we investigate whether GPX3 serum concentrations...
6.
Brune J, Kern M, Kunath A, Flehmig G, Schon M, Lohmann T, et al.
Obesity (Silver Spring) . 2015 Dec; 24(1):51-9. PMID: 26647900
Objective: Independent previous studies in both rodents and humans suggest a role of developmental genes in the origin of obesity and body fat distribution. Here, the hypothesis that human adipose...
7.
Mardinoglu A, Heiker J, Gartner D, Bjornson E, Schon M, Flehmig G, et al.
Sci Rep . 2015 Oct; 5:14841. PMID: 26434764
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in AT gene expression profiles particularly in visceral AT (VAT) have not been systematically studied. Here,...
8.
Lakowa N, Trieu N, Flehmig G, Lohmann T, Schon M, Dietrich A, et al.
Biochem Biophys Res Commun . 2015 Jan; 457(3):426-32. PMID: 25596130
Adipocyte hypertrophy and hyperplasia have been shown to be associated with shorter telomere length, which may reflect aging, altered cell proliferation and adipose tissue (AT) dysfunction. In individuals with obesity,...
9.
Flehmig G, Scholz M, Kloting N, Fasshauer M, Tonjes A, Stumvoll M, et al.
PLoS One . 2014 Jun; 9(6):e99785. PMID: 24968098
In obesity, elevated fat mass and ectopic fat accumulation are associated with changes in adipokine secretion, which may link obesity to inflammation and the development of insulin resistance. However, relationships...
10.
Kern M, Kosacka J, Hesselbarth N, Bruckner J, Heiker J, Flehmig G, et al.
Diabetes . 2014 Apr; 63(10):3295-309. PMID: 24760138
Replication initiator 1 (Repin1) is a zinc finger protein highly expressed in liver and adipose tissue and maps within a quantitative trait locus (QTL) for body weight and triglyceride (TG)...