Gert E Folkers
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Explore the profile of Gert E Folkers including associated specialties, affiliations and a list of published articles.
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44
Citations
740
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Recent Articles
1.
Dzurov Krafcikova M, Beriashvili D, Bahri S, Bergmeijer M, Howes S, Howes S, et al.
Angew Chem Int Ed Engl
. 2025 Mar;
:e202424131.
PMID: 40052409
Mitochondria are central to cellular bioenergetics, with the unique ability to translate and transcribe a subset of their own proteome. Given the critical importance of energy production, mitochondria seem to...
2.
Beriashvili D, Folkers G, Baldus M
Chembiochem
. 2024 Aug;
25(24):e202400508.
PMID: 39140844
Visualizing a protein's molecular motions has been a long standing topic of research in the biophysics community. Largely this has been done by exploiting nuclear magnetic resonance spectroscopy (NMR), and...
3.
Beriashvili D, Zhou J, Liu Y, Folkers G, Baldus M
Chemistry
. 2024 Mar;
30(28):e202400323.
PMID: 38451060
Sensitivity enhanced dynamic nuclear polarization solid-state NMR is emerging as a powerful technique for probing the structural properties of conformationally homogenous and heterogenous biomolecular species irrespective of size at atomic...
4.
Romanuka J, Folkers G, Gnida M, Kovacic L, Wienk H, Kaptein R, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(49):e2311240120.
PMID: 38019859
High-resolution NMR spectroscopy enabled us to characterize allosteric transitions between various functional states of the dimeric Lac repressor. In the absence of ligands, the dimer exists in a dynamic equilibrium...
5.
Beriashvili D, Yao R, DAmico F, Krafcikova M, Gurinov A, Safeer A, et al.
Chem Sci
. 2023 Sep;
14(36):9892-9899.
PMID: 37736634
Studying the structural aspects of proteins within sub-cellular compartments is of growing interest. Dynamic nuclear polarization supported solid-state NMR (DNP-ssNMR) is uniquely suited to provide such information, but critically lacks...
6.
le Paige U, Xiang S, Hendrix M, Zhang Y, Folkers G, Weingarth M, et al.
Magn Reson (Gott)
. 2022 Jun;
2(1):187-202.
PMID: 35647606
Regulation of DNA-templated processes such as gene transcription and DNA repair depend on the interaction of a wide range of proteins with the nucleosome, the fundamental building block of chromatin....
7.
Narasimhan S, Pinto C, Lucini Paioni A, van der Zwan J, Folkers G, Baldus M
Nat Protoc
. 2021 Jan;
16(2):893-918.
PMID: 33442051
For a long time, solid-state nuclear magnetic resonance (ssNMR) has been employed to study complex biomolecular systems at the detailed chemical, structural, or dynamic level. Recent progress in high-resolution and...
8.
Narasimhan S, Folkers G, Baldus M
Chempluschem
. 2020 Apr;
85(4):760-768.
PMID: 32297474
Solution-state NMR spectroscopy has become a powerful tool to study soluble proteins in cells, provided that they tumble sufficiently fast. In addition, cryo-electron tomography (cryo-ET) has recently displayed a tremendous...
9.
Narasimhan S, Scherpe S, Lucini Paioni A, van der Zwan J, Folkers G, Ovaa H, et al.
Angew Chem Int Ed Engl
. 2019 Jun;
58(37):12969-12973.
PMID: 31233270
Elucidating at atomic level how proteins interact and are chemically modified in cells represents a leading frontier in structural biology. We have developed a tailored solid-state NMR spectroscopic approach that...
10.
Faridounnia M, Folkers G, Boelens R
Molecules
. 2018 Dec;
23(12).
PMID: 30563071
Numerous proteins are involved in the multiple pathways of the DNA damage response network and play a key role to protect the genome from the wide variety of damages that...