Gerard Schellenberg
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Explore the profile of Gerard Schellenberg including associated specialties, affiliations and a list of published articles.
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28
Citations
864
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Recent Articles
1.
Godrich D, Pasteris J, Martin E, Rundek T, Schellenberg G, Foroud T, et al.
Brain Commun
. 2024 Nov;
6(6):fcae369.
PMID: 39584156
Cerebral amyloid angiopathy commonly co-occurs with amyloid β plaques and neurofibrillary degeneration and is proposed to contribute to cognitive impairment. However, the interplay among these pathologic changes of Alzheimer disease...
2.
Farrell K, Humphrey J, Chang T, Zhao Y, Leung Y, Kuksa P, et al.
Nat Commun
. 2024 Nov;
15(1):9828.
PMID: 39537593
No abstract available.
3.
Kuzma A, Valladares O, Greenfest-Allen E, Nicaretta H, Kirsch M, Ren Y, et al.
medRxiv
. 2024 Oct;
PMID: 39417134
NIAGADS is the National Institute on Aging (NIA) designated national data repository for human genetics research on Alzheimer's Disease and related dementia (ADRD). NIAGADS maintains a high-quality data collection for...
4.
Farrell K, Humphrey J, Chang T, Zhao Y, Leung Y, Kuksa P, et al.
Nat Commun
. 2024 Sep;
15(1):7880.
PMID: 39251599
Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from Alzheimer's disease (AD) and other diseases, displaying abnormal microtubule-associated protein...
5.
Cruchaga C, Bradley J, Western D, Wang C, Lucio Da Fonseca E, Neupane A, et al.
Res Sq
. 2024 Jun;
PMID: 38883718
Alzheimer Disease (AD) is a highly polygenic disease that presents with relatively earlier onset (≤70yo; EOAD) in about 5% of cases. Around 90% of these EOAD cases remain unexplained by...
6.
Lee W, Wang H, Dombroski B, Cheng P, Tucci A, Si Y, et al.
Res Sq
. 2023 Oct;
PMID: 37886469
Structural variations (SVs) are important contributors to the genetics of human diseases. However, their role in Alzheimer's disease (AD) remains largely unstudied due to challenges in accurately detecting SVs. We...
7.
Greenfest-Allen E, Valladares O, Kuksa P, Gangadharan P, Lee W, Cifello J, et al.
Alzheimers Dement
. 2023 Oct;
20(2):1123-1136.
PMID: 37881831
Introduction: The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site Alzheimer's Genomics Database (GenomicsDB) is a public knowledge base of Alzheimer's disease (AD) genetic datasets and genomic...
8.
Bai H, Naj A, Benchek P, Dumitrescu L, Hohman T, Hamilton-Nelson K, et al.
Alzheimers Dement
. 2023 Apr;
19(11):4886-4895.
PMID: 37051669
Background: Haptoglobin (HP) is an antioxidant of apolipoprotein E (APOE), and previous reports have shown HP binds with APOE and amyloid beta (Aβ) to aid its clearance. A common structural...
9.
Wang H, Wang L, Schellenberg G, Lee W
Front Aging Neurosci
. 2023 Feb;
14:1073905.
PMID: 36846102
Dozens of single nucleotide polymorphisms (SNPs) related to Alzheimer's disease (AD) have been discovered by large scale genome-wide association studies (GWASs). However, only a small portion of the genetic component...
10.
Vardarajan B, Reyes-Dumeyer D, Piriz A, Lantigua R, Medrano M, Rivera D, et al.
Alzheimers Dement
. 2022 Mar;
18(12):2458-2467.
PMID: 35258170
Introduction: Progranulin (GRN) mutations occur in frontotemporal lobar degeneration (FTLD) and in Alzheimer's disease (AD), often with TDP-43 pathology. Methods: We determined the frequency of rs5848 and rare, pathogenic GRN...