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Gerard N Bischof

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Articles 47
Citations 1127
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Recent Articles
1.
Bischof G, Jaeger E, Giehl K, Jessen F, Onur O, OBryant S, et al.
Neurology . 2024 Dec; 103(12):e210062. PMID: 39626130
Background And Objectives: Apraxia is a frequently observed symptom in Alzheimer disease (AD), but the causal pathomechanism underlying this dysfunction is not well understood. Previous studies have demonstrated associations between...
2.
Collij L, Bischof G, Altomare D, Bader I, Battle M, Garcia D, et al.
J Nucl Med . 2024 Nov; 66(1):110-116. PMID: 39542700
Several studies have demonstrated strong agreement between routine clinical visual assessment and quantification, suggesting that quantification approaches could support assessment by less experienced readers or in challenging cases. However, all...
3.
Beer S, Elmenhorst D, Bischof G, Ramirez A, Bauer A, Drzezga A
Neurobiol Aging . 2024 Aug; 143:19-29. PMID: 39208715
Aquaporin-4 (AQP4) is hypothesized to be a component of the glymphatic system, a pathway for removing brain interstitial solutes like amyloid-β (Aβ). Evidence exists that genetic variation of AQP4 impacts...
4.
Theis H, Barbe M, Drzezga A, Fink G, Neumaier B, Bischof G, et al.
J Parkinsons Dis . 2024 Jul; 14(6):1271-1276. PMID: 38995804
In progressive supranuclear palsy (PSP), subcortical tau and cortical perfusion can be assessed using the tracer [18F]PI-2620. We investigated if subcortical tau (globus pallidus internus, dentate nucleus) and frontal/limbic perfusion...
5.
Dzialas V, Hoenig M, Prange S, Bischof G, Drzezga A, van Eimeren T
NPJ Parkinsons Dis . 2024 May; 10(1):94. PMID: 38697984
Resilience in neuroscience generally refers to an individual's capacity to counteract the adverse effects of a neuropathological condition. While resilience mechanisms in Alzheimer's disease are well-investigated, knowledge regarding its quantification,...
6.
Bischof G, Jaeger E, Giehl K, Jessen F, Onur O, OBryant S, et al.
medRxiv . 2024 Apr; PMID: 38645131
Objectives: Apraxia is a core feature of Alzheimer's disease, but the pathomechanism of this characteristic symptom is not well understood. Here, we systematically investigated apraxia profiles in a well-defined group...
7.
Bischof G, Brendel M, Barthel H, Theis H, Barbe M, Bartenstein P, et al.
J Nucl Med . 2024 Apr; 65(6):952-955. PMID: 38575191
We used a new data-driven methodology to identify a set of reference regions that enhanced the quantification of the SUV ratio of the second-generation tau tracer 2-(2-([F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([F]PI-2620) in a...
8.
Jaeger E, Bischof G, Onur O, Schlamann M, Drzezga A
Eur J Nucl Med Mol Imaging . 2024 Mar; 51(8):2515-2516. PMID: 38433149
No abstract available.
9.
Honig M, Altomare D, Caprioglio C, Collij L, Barkhof F, van Berckel B, et al.
Neurology . 2024 Feb; 102(6):e208053. PMID: 38377442
Objectives: Higher-educated patients with Alzheimer disease (AD) can harbor greater neuropathologic burden than those with less education despite similar symptom severity. In this study, we assessed whether this observation is...
10.
Bischof G, Jaeger E, Giehl K, Honig M, Weiss P, Drzezga A
eNeuro . 2024 Jan; 11(1). PMID: 38164539
Stereotypical isocortical tau protein pathology along the Braak stages has been described as an instigator of neurodegeneration in Alzheimer's disease (AD). Less is known about tau pathology in motor regions,...