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Gerald Wallweber

Explore the profile of Gerald Wallweber including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 158
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Recent Articles
1.
Bauman J, Ohr J, Gooding W, Ferris R, Duvvuri U, Kim S, et al.
Cancers (Basel) . 2020 Jun; 12(6). PMID: 32545260
Cetuximab, an anti-EGFR monoclonal antibody (mAb), is approved for advanced head and neck squamous cell carcinoma (HNSCC) but benefits a minority. An established tumor-intrinsic resistance mechanism is cross-talk between the...
2.
Alvarado D, Ligon G, Lillquist J, Seibel S, Wallweber G, Neumeister V, et al.
PLoS One . 2017 Jul; 12(7):e0181356. PMID: 28723928
Head and neck squamous cell carcinoma (HNSCC) accounts for 3-5% of all tumor types and remains an unmet medical need with only two targeted therapies approved to date. ErbB3 (HER3),...
3.
Chumsri S, Weidler J, Ali S, Balasubramanian S, Wallweber G, DeFazio-Eli L, et al.
J Natl Compr Canc Netw . 2015 Sep; 13(9):1066-70. PMID: 26358791
In the current genomic era, increasing evidence demonstrates that approximately 2% of HER2-negative breast cancers, by current standard testings, harbor activating mutations of ERBB2. However, whether patients with HER2-negative breast...
4.
Pollock N, Wang L, Wallweber G, Gooding W, Huang W, Chenna A, et al.
Clin Cancer Res . 2015 Jul; 21(20):4597-606. PMID: 26138066
Purpose: In other cancer types, HPV infection has been reported to coincide with overexpression of HER2 (ERBB2) and HER3 (ERBB3); however, the association between HER2 or HER3 expression and dimer...
5.
Shi Y, Huang W, Tan Y, Jin X, Dua R, Penuel E, et al.
Diagn Mol Pathol . 2009 Feb; 18(1):11-21. PMID: 19214113
The availability of drugs targeting the EGFR/HER/erbB signaling pathway has created a need for diagnostics that accurately predict treatment responses. We have developed and characterized a novel assay to provide...
6.
Wallweber G, Gryaznov S, Pongracz K, Pruzan R
Biochemistry . 2003 Jan; 42(2):589-600. PMID: 12525188
Telomerase is a ribonucleoprotein responsible for maintaining the ends of linear chromosomes in nearly all eukaryotic cells. In humans, expression of the enzyme is limited primarily to the germ line...
7.
Pruzan R, Pongracz K, Gietzen K, Wallweber G, Gryaznov S
Nucleic Acids Res . 2002 Jan; 30(2):559-68. PMID: 11788719
Telomerase is a ribonucleoprotein responsible for maintaining telomeres in nearly all eukaryotic cells. The enzyme is able to utilize a short segment of its RNA subunit as the template for...