Gerald E McClearn
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Explore the profile of Gerald E McClearn including associated specialties, affiliations and a list of published articles.
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33
Citations
550
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Recent Articles
1.
McClearn G, McCarter R
ILAR J
. 2011 Mar;
52(1):16-23.
PMID: 21411854
There are advantages and limitations to using genetically heterogeneous stocks and selective breeding procedures in gerontological and health span research. Animal models that address complex systems of aging involve constraint...
2.
Sloane L, Stout J, Austad S, McClearn G
J Gerontol A Biol Sci Med Sci
. 2010 Nov;
66(3):287-94.
PMID: 21059835
Research has attempted to identify biomarkers of aging that are predictive of longevity and specific age-related changes during animal life span. Tail tendon break time (TTBT), one presumed biomarker, measures...
3.
Sloane L, Stout J, Vandenbergh D, Vogler G, Gerhard G, McClearn G
J Gerontol A Biol Sci Med Sci
. 2010 Nov;
66(2):170-8.
PMID: 21047976
Tail tendon break time (TTBT), a measure of collagen cross-linking, shown to increase with age differs significantly among inbred strains of mice, indicating underlying genetic influences. This study was aimed...
4.
Lang D, Gerhard G, Griffith J, Vogler G, Vandenbergh D, Blizard D, et al.
Aging Clin Exp Res
. 2010 Mar;
22(1):8-19.
PMID: 20305363
Background And Aims: Genes associated with longevity have been identified using both single gene and genome-wide approaches in a variety of species. The aim of this study was to identify...
5.
Lionikas A, Carlborg O, Lu L, Peirce J, Williams R, Yu F, et al.
J Hered
. 2010 Mar;
101(3):360-7.
PMID: 20233743
The precise locations of attachment points of muscle to bone-the origin and insertion sites-are crucial anatomical and functional characteristics that influence locomotor performance. Mechanisms that control the development of these...
6.
Vasilopoulos T, Mack H, McClearn G, Berg S, Johansson B, Vogler G
Am J Hum Biol
. 2009 Oct;
22(3):375-7.
PMID: 19844901
Using data from the first four waves of the OCTO-Twin study (twins 80 + years), the present study investigated the stability and change of genetic and environmental contributions to pulmonary...
7.
Lang D, Conroy D, Lionikas A, Mack H, Larsson L, Vogler G, et al.
J Bone Miner Res
. 2009 May;
24(9):1608-17.
PMID: 19419307
Correlations among bone strength, muscle mass, and physical activity suggest that these traits may be modulated by each other and/or by common genetic and/or environmental mechanisms. This study used structural...
8.
Berg A, Hoffman L, Hassing L, McClearn G, Johansson B
Aging Ment Health
. 2009 Apr;
13(2):191-201.
PMID: 19347686
Objectives: The study investigates whether markers of life satisfaction identified in a cross-sectional study-quality of social network, self-rated health, depressive symptoms, locus of control and widowhood, in addition to financial...
9.
Blizard D, Lionikas A, Vandenbergh D, Vasilopoulos T, Gerhard G, Griffith J, et al.
Physiol Genomics
. 2008 Dec;
36(3):158-66.
PMID: 19066325
A quantitative trait locus (QTL) approach was used to define the genetic architecture underlying variation in systolic blood pressure (SBP) and heart rate (HR), measured indirectly on seven occasions by...
10.
Blizard D, Vandenbergh D, Lionikas A, McClearn G
Alcohol Clin Exp Res
. 2008 Oct;
32(12):2041-6.
PMID: 18828810
Background: The 2-bottle preference test is a popular protocol for characterizing a rodent's selection of a variety of solutions. Little attention has been paid, however, to the role of learning...