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Arimantas Lionikas

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Articles 39
Citations 482
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Recent Articles
1.
Papadam A, Lionikas A, Grassmann F
Aging Cell . 2025 Jan; :e14473. PMID: 39757747
Age-related macular degeneration (AMD) is a progressive disorder and the leading cause of central vision loss. Age is the most important risk factor, followed by genetics and smoking. However, ageing...
2.
Lekkos K, Bhuiyan A, Albloshi A, Brooks P, Coate T, Lionikas A
G3 (Bethesda) . 2024 Apr; 14(5). PMID: 38577978
Genetic variability significantly contributes to individual differences in skeletal muscle mass; however, the specific genes involved in that process remain elusive. In this study, we examined the role of positional...
3.
Lionikas A, Hernandez Cordero A, Kilikevicius A, Carroll A, Bewick G, Bunger L, et al.
Physiol Rep . 2023 Aug; 11(15):e15793. PMID: 37568262
Aims: Stanniocalcin-2 (STC2) has recently been implicated in human muscle mass variability by genetic analysis. Biochemically, STC2 inhibits the proteolytic activity of the metalloproteinase PAPP-A, which promotes muscle growth by...
4.
Zou J, Gopalakrishnan S, Parker C, Nicod J, Mott R, Cai N, et al.
G3 (Bethesda) . 2021 Nov; 12(1). PMID: 34791208
Combining samples for genetic association is standard practice in human genetic analysis of complex traits, but is rarely undertaken in rodent genetics. Here, using 23 phenotypes and genotypes from two...
5.
Hernandez Cordero A, Gonzales N, Parker C, Sokoloff G, Vandenbergh D, Cheng R, et al.
Am J Hum Genet . 2020 Jan; 106(1):138. PMID: 31901248
No abstract available.
6.
Hernandez Cordero A, Gonzales N, Parker C, Sokolof G, Vandenbergh D, Cheng R, et al.
Am J Hum Genet . 2019 Nov; 105(6):1222-1236. PMID: 31761296
Muscle bulk in adult healthy humans is highly variable even after height, age, and sex are accounted for. Low muscle mass, due to fewer and/or smaller constituent muscle fibers, would...
7.
Kvedaras M, Minderis P, Krusnauskas R, Lionikas A, Ratkevicius A
Exp Gerontol . 2019 Oct; 128:110751. PMID: 31654693
Myostatin is an inhibitor of skeletal muscle growth and might be involved in adaptations to caloric restriction (CR). We compared responses to 12-week 30% CR in male mice of Berlin...
8.
Fokin A, Minderis P, Venckunas T, Lionikas A, Kvedaras M, Ratkevicius A
J Musculoskelet Neuronal Interact . 2019 Sep; 19(3):342-353. PMID: 31475942
Objectives: The aim of the study was to investigate if myostatin dysfunction can ameliorate fasting-induced muscle wasting. Methods: 18-week old males from Berlin high (BEH) strain with myostatin dysfunction and...
9.
Alhindi Y, VaanHolt L, Al-Tarrah M, Gray S, Speakman J, Hambly C, et al.
J Nutr Metab . 2019 Aug; 2019:9153809. PMID: 31467706
[This corrects the article DOI: 10.1155/2019/8594825.].
10.
Alhindi Y, VaanHolt L, Al-Tarrah M, Gray S, Speakman J, Hambly C, et al.
J Nutr Metab . 2019 Apr; 2019:8594825. PMID: 30944739
Citrate synthase (CS) is a key mitochondrial enzyme. The aim of this study was to test the hypothesis that low CS activity impairs the metabolic health of mice fed a...