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Georgios Skretas

Explore the profile of Georgios Skretas including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 449
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Recent Articles
1.
Rigkos K, Filis G, Antonopoulou I, de Oliveira Maciel A, Saridis P, Zarafeta D, et al.
Environ Sci Technol . 2024 Sep; 58(40):17732-17742. PMID: 39311668
Taking immediate action to combat the urgent threat of CO-driven global warming is crucial for ensuring a habitable planet. Decarbonizing the industrial sector requires implementing sustainable carbon-capture technologies, such as...
2.
Tsekrekou M, Giannakou M, Papanikolopoulou K, Skretas G
Front Mol Biosci . 2024 Jun; 11:1383453. PMID: 38855322
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with severe socio-economic impact. A hallmark of ALS pathology is the presence of aberrant cytoplasmic inclusions composed of misfolded and aggregated...
3.
Papadopoulou D, Mavrikaki V, Charalampous F, Tzaferis C, Samiotaki M, Papavasileiou K, et al.
Angew Chem Int Ed Engl . 2024 Feb; 63(14):e202319157. PMID: 38339863
Fibroblasts are key regulators of inflammation, fibrosis, and cancer. Targeting their activation in these complex diseases has emerged as a novel strategy to restore tissue homeostasis. Here, we present a...
4.
Vasilopoulou E, Chroumpi T, Skretas G
Protein Sci . 2023 Dec; 33(2):e4864. PMID: 38073126
Escherichia coli is one of the most widely utilized hosts for production of recombinant membrane proteins (MPs). Bacterial MP production, however, is usually accompanied by severe toxicity and low-level volumetric...
5.
Papanikolaou A, Chatzikonstantinou A, Zarafeta D, Kourkoumelis N, Skretas G, Pavlidis I, et al.
Chembiochem . 2022 Dec; 24(5):e202200642. PMID: 36545817
Esterases are among the most studied enzymes, and their applications expand into several branches of industrial biotechnology. Yet, despite the fact that information on their substrate specificity is crucial for...
6.
Vasilopoulou E, Giannakopoulou A, Kapsalis C, Michou M, Michoglou-Sergiou A, Kolisis F, et al.
ACS Synth Biol . 2022 Aug; 11(8):2599-2609. PMID: 35922033
is one of the most widely utilized hosts for recombinant protein production, including that of membrane proteins (MPs). We have recently engineered a specialized strain for enhanced recombinant MP production,...
7.
Delivoria D, Skretas G
Methods Mol Biol . 2021 Oct; 2371:215-246. PMID: 34596851
The phenomenon of protein misfolding and aggregation has been widely associated with numerous human diseases, such as Alzheimer's disease, systemic amyloidosis and type 2 diabetes, the vast majority of which...
8.
Michou M, Delivoria D, Skretas G
Bio Protoc . 2021 Mar; 10(15):e3710. PMID: 33659374
We have previously described the development of two specialized strains for high-level recombinant membrane protein (MP) production. These engineered strains, termed SuptoxD and SuptoxR, are capable of suppressing the cytotoxicity...
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Myrtollari K, Katsoulakis N, Zarafeta D, Pavlidis I, Skretas G, Smonou I
Bioorg Chem . 2020 Sep; 104:104214. PMID: 32927128
In this paper, we study the activity and specificity of EstDZ2, a new thermostable carboxyl esterase of unknown function, which was isolated from a metagenome library from a Russian hot...