Georgette Moyle-Heyrman
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Explore the profile of Georgette Moyle-Heyrman including associated specialties, affiliations and a list of published articles.
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9
Citations
176
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Recent Articles
1.
Moore L, Caldwell M, Townsend T, MacRenaris K, Moyle-Heyrman G, Rammohan N, et al.
Bioconjug Chem
. 2019 Oct;
30(11):2947-2957.
PMID: 31589412
ProGlo is an efficient steroid receptor-targeted magnetic resonance (MR) imaging contrast agent (CA). It has been shown to bind to the progesterone receptor (PR) and produce enhanced image contrast in...
2.
Young A, Moyle-Heyrman G, Kim J, Burdette J
Exp Biol Med (Maywood)
. 2017 Oct;
242(17):1690-1700.
PMID: 29065798
Microphysiologic systems (MPS), including new organ-on-a-chip technologies, recapitulate tissue microenvironments by employing specially designed tissue or cell culturing techniques and microfluidic flow. Such systems are designed to incorporate physiologic factors...
3.
Moyle-Heyrman G, Schipma M, Dean M, Davis D, Burdette J
J Ovarian Res
. 2016 Feb;
9:5.
PMID: 26879975
Background: The fallopian tube epithelium is one of the potential sources of high-grade serous ovarian cancer (HGSC). The use of estrogen only hormone replacement therapy increases ovarian cancer (OVCA) risk....
4.
Endsley M, Moyle-Heyrman G, Karthikeyan S, Lantvit D, Davis D, Wei J, et al.
Front Oncol
. 2015 Aug;
5:154.
PMID: 26236688
High-grade serous carcinoma (HGSC) is the most lethal ovarian cancer histotype. The fallopian tube secretory epithelial cells (FTSECs) are a proposed progenitor cell type. Genetically altered FTSECs form tumors in...
5.
Eddie S, Quartuccio S, O hAinmhir E, Moyle-Heyrman G, Lantvit D, Wei J, et al.
Oncotarget
. 2015 May;
6(24):20500-12.
PMID: 25971410
Ovarian cancer is the most lethal gynecological malignancy, primarily because its origin and initiation factors are unknown. A secretory murine oviductal epithelial (MOE) model was generated to address the hypothesis...
6.
Townsend T, Moyle-Heyrman G, Sukerkar P, MacRenaris K, Burdette J, Meade T
Bioconjug Chem
. 2014 Jul;
25(8):1428-37.
PMID: 25019183
Determination of progesterone receptor (PR) status in hormone-dependent diseases is essential in ascertaining disease prognosis and monitoring treatment response. The development of a noninvasive means of monitoring these processes would...
7.
Moyle-Heyrman G, Zaichuk T, Xi L, Zhang Q, Uhlenbeck O, Holmgren R, et al.
Proc Natl Acad Sci U S A
. 2013 Nov;
110(50):20158-63.
PMID: 24277842
Using a recently developed chemical approach, we have generated a genome-wide map of nucleosomes in vivo in Schizosaccharomyces pombe (S. pombe) at base pair resolution. The shorter linker length previously...
8.
Moyle-Heyrman G, Viswanathan R, Widom J, Auble D
J Biol Chem
. 2012 Feb;
287(12):9002-12.
PMID: 22298788
The TATA box binding protein (TBP) is a central component of the transcription preinitiation complex, and its occupancy at a promoter is correlated with transcription levels. The TBP-promoter DNA complex...
9.
Moyle-Heyrman G, Tims H, Widom J
J Mol Biol
. 2011 Aug;
412(4):634-46.
PMID: 21821044
Cooperativity in transcription factor (TF) binding is essential in eukaryotic gene regulation and arises through diverse mechanisms. Here, we focus on one mechanism, collaborative competition, which is of interest because...