George Zogopoulos
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Explore the profile of George Zogopoulos including associated specialties, affiliations and a list of published articles.
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63
Citations
2915
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Recent Articles
11.
Wang Y, Cuggia A, Chen Y, Parent J, Stanek A, Denroche R, et al.
J Natl Compr Canc Netw
. 2022 Jun;
20(6):663-673.e12.
PMID: 35714671
Background: Individuals with a family history of pancreatic adenocarcinoma (PC) or with a germline mutation in a PC susceptibility gene are at increased risk of developing PC. These high-risk individuals...
12.
OKane G, Grunwald B, Jang G, Masoomian M, Picardo S, Grant R, et al.
Clin Cancer Res
. 2022 Jun;
28(12):2715.
PMID: 35694787
No abstract available.
13.
Alghamdi A, Palmieri V, Alotaibi N, Barkun A, Zogopoulos G, Chaudhury P, et al.
J Can Assoc Gastroenterol
. 2022 Jun;
5(3):121-128.
PMID: 35669844
Background And Aim: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the standard of care in advanced pancreatic cancer. Its role in resectable disease, however, is controversial. This meta-analysis aims to...
14.
Golesworthy B, Wang Y, Tanti A, Pacis A, Romero J, Cuggia A, et al.
Front Oncol
. 2022 May;
12:860767.
PMID: 35547873
The immune contexture of pancreatic ductal adenocarcinoma (PDAC) is generally immunosuppressive. A role for immune checkpoint inhibitors (ICIs) in PDAC has only been demonstrated for the rare and hypermutated mismatch...
15.
Smith A, Wong C, Cuggia A, Borgida A, Holter S, Hall A, et al.
JCO Precis Oncol
. 2022 Feb;
2:1-16.
PMID: 35135108
Purpose: We investigated the translational value of reflex testing for germline mutations in four homology-directed DNA repair predisposition genes (, , , and ) in consecutive patients with pancreatic adenocarcinoma....
16.
Meti N, Kelly D, Allen M, Lanys A, Fazelzad R, Ramjeesingh R, et al.
Cancer Treat Rev
. 2021 Nov;
101:102310.
PMID: 34757307
Purpose: Current guidelines recommend somatic genomic sequencing for patients with advanced pancreatic cancer to identify targetable alterations amenable to targeted therapy. The benefit of somatic genomic sequencing in pancreatic cancer...
17.
Wang Y, Golesworthy B, Cuggia A, Domecq C, Chaudhury P, Barkun J, et al.
J Med Genet
. 2021 Sep;
59(8):793-800.
PMID: 34556502
Background: Traditional medical genetics models are unable to meet the growing demand for germline genetic testing (GT) in patients with exocrine pancreatic cancer (PC). This study investigates the impact of...
18.
Hsu F, Roberts N, Childs E, Porter N, Rabe K, Borgida A, et al.
JAMA Oncol
. 2021 Sep;
7(11):1664-1668.
PMID: 34529012
Importance: Pathogenic germline variants in the ATM gene have been associated with pancreatic cancer risk. Although genetic testing identifies these variants in approximately 1% to 3% of unselected patients with...
19.
Wang Y, Cuggia A, Pacis A, Boileau J, Marcus V, Gao Z, et al.
J Natl Compr Canc Netw
. 2021 Aug;
19(8):883-887.
PMID: 34416708
Pancreatic ductal adenocarcinomas (PDACs) with DNA mismatch repair deficiency (MMRd) respond preferentially to immune checkpoint inhibitors (ICIs). However, a subset of MMRd PDACs does not respond to these agents. This...
20.
Zhang H, Corredor A, Messina-Pacheco J, Li Q, Zogopoulos G, Kaddour N, et al.
Commun Biol
. 2021 Jun;
4(1):688.
PMID: 34099862
Persistent acinar to ductal metaplasia (ADM) is a recently recognized precursor of pancreatic ductal adenocarcinoma (PDAC). Here we show that the ADM area of human pancreas tissue adjacent to PDAC...