George Stamatoyannopoulos
Overview
Explore the profile of George Stamatoyannopoulos including associated specialties, affiliations and a list of published articles.
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77
Citations
4008
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Recent Articles
1.
Papayanni P, Psatha N, Christofi P, Li X, Melo P, Volpin M, et al.
Hum Gene Ther
. 2021 Sep;
32(19-20):1186-1199.
PMID: 34477013
Despite the unequivocal success of hematopoietic stem and progenitor cell gene therapy, limitations still exist including genotoxicity and variegation/silencing of transgene expression. A class of DNA regulatory elements known as...
2.
Drineas P, Tsetsos F, Plantinga A, Lazaridis I, Yannaki E, Razou A, et al.
Ann Hum Genet
. 2019 Jun;
83(6):373-388.
PMID: 31192450
The medieval history of several populations often suffers from scarcity of contemporary records resulting in contradictory and sometimes biased interpretations by historians. This is the situation with the population of...
3.
Li C, Psatha N, Sova P, Gil S, Wang H, Kim J, et al.
Blood
. 2018 May;
131(26):2915-2928.
PMID: 29789357
Disorders involving β-globin gene mutations, primarily β-thalassemia and sickle cell disease, represent a major target for hematopoietic stem/progenitor cell (HSPC) gene therapy. This includes CRISPR/Cas9-mediated genome editing approaches in adult...
4.
Lazaridis I, Mittnik A, Patterson N, Mallick S, Rohland N, Pfrengle S, et al.
Nature
. 2017 Aug;
548(7666):214-218.
PMID: 28783727
The origins of the Bronze Age Minoan and Mycenaean cultures have puzzled archaeologists for more than a century. We have assembled genome-wide data from 19 ancient individuals, including Minoans from...
5.
Stamatoyannopoulos G, Bose A, Teodosiadis A, Tsetsos F, Plantinga A, Psatha N, et al.
Eur J Hum Genet
. 2017 Mar;
25(5):637-645.
PMID: 28272534
Peloponnese has been one of the cradles of the Classical European civilization and an important contributor to the ancient European history. It has also been the subject of a controversy...
6.
Constantinou V, Bouinta A, Karponi G, Zervou F, Papayanni P, Stamatoyannopoulos G, et al.
Transfusion
. 2016 Dec;
57(4):1031-1039.
PMID: 27987208
Background: Hematopoietic stem cell mobilization and leukapheresis in adult patients with β-thalassemia have recently been optimized in the context of clinical trials for obtaining hematopoietic stem cells for thalassemia gene...
7.
Mallick S, Li H, Lipson M, Mathieson I, Gymrek M, Racimo F, et al.
Nature
. 2016 Sep;
538(7624):201-206.
PMID: 27654912
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that...
8.
Vierstra J, Reik A, Chang K, Stehling-Sun S, Zhou Y, Hinkley S, et al.
Nat Methods
. 2015 Sep;
12(10):927-30.
PMID: 26322838
Regulatory regions harbor multiple transcription factor (TF) recognition sites; however, the contribution of individual sites to regulatory function remains challenging to define. We describe an approach that exploits the error-prone...
9.
Blobel G, Bodine D, Brand M, Crispino J, de Bruijn M, Nathan D, et al.
Exp Hematol
. 2015 Jul;
43(10):821-37.
PMID: 26143582
Every 2 years since 1978, an international group of scientists, physicians, and other researchers meet to discuss the latest developments in the underlying etiology, mechanisms of action, and developmental acquisition...
10.
Karponi G, Psatha N, Lederer C, Adair J, Zervou F, Zogas N, et al.
Blood
. 2015 Jun;
126(5):616-9.
PMID: 26089395
Globin gene therapy requires abundant numbers of highly engraftable, autologous hematopoietic stem cells expressing curative levels of β-globin on differentiation. In this study, CD34+ cells from 31 thalassemic patients mobilized...