George Santis
Overview
Explore the profile of George Santis including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
29
Citations
588
Followers
0
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Recent Articles
1.
Josephides E, Smith D, Bille A, Patel A, Rush H, Dunn R, et al.
Clin Lung Cancer
. 2025 Feb;
PMID: 39915192
Background: Immune checkpoint inhibitors have improved survival in patients with non-small cell lung cancer (NSCLC). Whilst PD-L1 expression is a useful predictive biomarker, data on concordance of expression between primary...
2.
Sekhawat V, van der Linde M, Routledge T, Santis G, Nonaka D
Int J Surg Pathol
. 2024 Jul;
:10668969241261541.
PMID: 39034412
Metaplastic thymoma is a rare thymic neoplasm that has generally been considered to follow a benign to indolent clinical course; however, 3 metaplastic thymomas with high-grade malignant transformation to sarcomatoid...
3.
Hughes D, Kapiris M, Podvez Nevajda A, McGrath H, Stavraka C, Ahmad S, et al.
Cancers (Basel)
. 2022 Dec;
14(24).
PMID: 36551542
(1) Background: Non-small cell lung cancer (NSCLC) in young patients is uncommon. Real-world evidence on the outcomes of these patients is limited. (2) Methods: We conducted a retrospective cohort study...
4.
Ortiz-Zapater E, Bagley D, Hernandez V, Roberts L, Maguire T, Voss F, et al.
Nat Commun
. 2022 Oct;
13(1):6407.
PMID: 36302767
Airway inflammation and remodelling are important pathophysiologic features in asthma and other respiratory conditions. An intact epithelial cell layer is crucial to maintain lung homoeostasis, and this depends on intercellular...
5.
Owczarek C, Ortiz-Zapater E, Kim J, Papaevangelou E, Santis G, Parsons M
Front Oncol
. 2022 Mar;
12:829313.
PMID: 35252000
The coxsackie and adenovirus receptor (CAR) is a member of the junctional adhesion molecule (JAM) family of adhesion receptors and is localised to epithelial cell tight and adherens junctions. CAR...
6.
Perumal P, Abdullatif M, Garlant H, Honeyborne I, Lipman M, McHugh T, et al.
Front Immunol
. 2021 Apr;
11:612564.
PMID: 33841389
Tuberculosis (TB) remains a major global threat and diagnosis of active TB ((ATB) both extra-pulmonary (EPTB), pulmonary (PTB)) and latent TB (LTBI) infection remains challenging, particularly in high-burden countries which...
7.
Al-Najjar H, Breen R, Santis G, Narayan O
Eur Respir J
. 2020 Jan;
55(4).
PMID: 31980494
No abstract available.
8.
The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers
Zanetti-Domingues L, Korovesis D, Needham S, Tynan C, Sagawa S, Roberts S, et al.
Nat Commun
. 2018 Oct;
9(1):4325.
PMID: 30337523
Our current understanding of epidermal growth factor receptor (EGFR) autoinhibition is based on X-ray structural data of monomer and dimer receptor fragments and does not explain how mutations achieve ligand-independent...
9.
Pike R, Ortiz-Zapater E, Lumicisi B, Santis G, Parsons M
Sci Signal
. 2018 Feb;
11(515).
PMID: 29382784
The coxsackievirus and adenovirus receptor (CAR) is a transmembrane receptor that plays a key role in cell-cell adhesion. CAR is found in normal epithelial cells and is increased in abundance...
10.
Ortiz-Zapater E, Santis G, Parsons M
Int J Biochem Cell Biol
. 2017 May;
89:1-5.
PMID: 28545889
The coxsackie and adenovirus receptor (CAR) is a transmembrane receptor that plays a key role in controlling adhesion between adjacent epithelial cells. CAR is highly expressed in epithelial cells and...