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George S Worthen

Explore the profile of George S Worthen including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 129
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Recent Articles
1.
Myerson J, Patel P, Rubey K, Zamora M, Zaleski M, Habibi N, et al.
Nat Nanotechnol . 2021 Nov; 17(1):86-97. PMID: 34795440
This study shows that the supramolecular arrangement of proteins in nanoparticle structures predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We observed homing to inflamed lungs for a...
2.
Issah Y, Naik A, Tang S, Forrest K, Brooks T, Lahens N, et al.
Elife . 2021 Mar; 10. PMID: 33650487
Adverse early-life exposures have a lasting negative impact on health. Neonatal hyperoxia that is a risk factor for bronchopulmonary dysplasia confers susceptibility to influenza A virus (IAV) infection later in...
3.
Liu Y, Perego M, Xiao Q, He Y, Fu S, He J, et al.
J Clin Invest . 2019 Sep; 129(10):4261-4275. PMID: 31483289
Inflammation plays a critical role in the development of severe neonatal morbidities. Myeloid-derived suppressor cells (MDSCs) were recently implicated in the regulation of immune responses in newborns. Here, we report...
4.
Laudanski K, Lapko N, Zawadka M, Zhou B, Danet-Desnoyers G, Worthen G
PLoS One . 2017 Jul; 12(7):e0180377. PMID: 28715505
Sepsis triggers a coordinated and thorough immune system response with long-term unfavorable sequelae after the initial insult. Long-term recovery from sepsis has garnered increasing attention recently, but a lack of...
5.
Lapko N, Zawadka M, Polosak J, Worthen G, Danet-Desnoyers G, Puzianowska-Kuznicka M, et al.
Front Immunol . 2017 May; 8:401. PMID: 28507543
The duration of post-sepsis long-term immune suppression is poorly understood. Here, we focused on the role of monocytes (MO) as the pivotal cells for long-term regulation of post-sepsis milieu. Lost...
6.
Laudanski K, Qing M, Oszkiel H, Zawadka M, Lapko N, Nowak Z, et al.
Anesthesiology . 2015 Jul; 123(3):628-41. PMID: 26197043
Background: Monocytes (MOs) have the unique ability to differentiate into immature dendritic cells (iDCs) (MO→iDC) under the influence of interleukin-4 and granulocyte-monocyte colony-stimulating factor (IL-4&GM-CSF). In this study, the authors...
7.
Floros J, Londono D, Gordon D, Silveyra P, DiAngelo S, Viscardi R, et al.
Pediatr Res . 2012 Feb; 71(1):107-14. PMID: 22289858
Introduction: The genetic contribution to the development of bronchopulmonary dysplasia (BPD) in prematurely born infants is substantial, but information related to the specific genes involved is lacking. Results: Genotype analysis...