George S Robertson
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Explore the profile of George S Robertson including associated specialties, affiliations and a list of published articles.
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56
Citations
863
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Recent Articles
11.
Novorolsky R, Nichols M, Kim J, Pavlov E, Woods J, Wilson J, et al.
J Cereb Blood Flow Metab
. 2020 Mar;
40(6):1172-1181.
PMID: 32126877
The mitochondrial calcium (Ca) uniporter (MCU) mediates high-capacity mitochondrial Ca uptake implicated in ischemic/reperfusion cell death. We have recently shown that inducible MCU ablation in Thy1-expressing neurons renders mice resistant...
12.
Lamport A, Chedrawe M, Nichols M, Robertson G
J Neuroimmunol
. 2019 Jun;
334:576995.
PMID: 31228686
Experimental autoimmune encephalomyelitis (EAE) and lysophosphatidylcholine (LPC)-induced demyelination were combined to study remyelination in a pro-inflammatory context. Two groups of female C57BL/6 mice were subjected either to EAE (EAE mice)...
13.
Ploughman M, Eskes G, Kelly L, Kirkland M, Devasahayam A, Wallack E, et al.
Neurorehabil Neural Repair
. 2019 Mar;
33(3):199-212.
PMID: 30816066
Background: Paired exercise and cognitive training have the potential to enhance cognition by "priming" the brain and upregulating neurotrophins. Methods: Two-site randomized controlled trial. Fifty-two patients >6 months poststroke with...
14.
Chedrawe M, Holman S, Lamport A, Akay T, Robertson G
J Neuroimmunol
. 2018 Jun;
321:72-82.
PMID: 29957391
Recent evidence suggests that clozapine and quetiapine (atypical antipsychotics), tamoxifen (selective-estrogen receptor modulator) and pioglitazone (PPARγ agonist) may improve functional recovery in multiple sclerosis (MS). We have compared the effectiveness...
15.
Nichols M, Pavlov E, Robertson G
Cell Death Dis
. 2018 May;
9(6):606.
PMID: 29789575
The mitochondrial calcium uniporter (MCU) mediates high-capacity mitochondrial calcium uptake that stimulates energy production. However, excessive MCU activity can cause ischemic heart injury. To examine if the MCU is also...
16.
Fiander M, Chedrawe M, Lamport A, Akay T, Robertson G
J Vis Exp
. 2017 Nov;
(129).
PMID: 29155752
Kinematic gait analysis in the sagittal plane has frequently been used to characterize motor deficits in multiple sclerosis (MS). We describe the application of these techniques to identify gait deficits...
17.
Nichols M, Elustondo P, Warford J, Thirumaran A, Pavlov E, Robertson G
J Cereb Blood Flow Metab
. 2016 Dec;
37(8):3027-3041.
PMID: 27909264
The effects of global mitochondrial calcium (Ca) uniporter (MCU) deficiency on hypoxic-ischemic (HI) brain injury, neuronal Ca handling, bioenergetics and hypoxic preconditioning (HPC) were examined. Forebrain mitochondria isolated from global...
18.
Elustondo P, Nichols M, Robertson G, Pavlov E
J Bioenerg Biomembr
. 2016 Sep;
49(1):113-119.
PMID: 27665468
Calcium (Ca) plays diverse roles in all living organisms ranging from bacteria to humans. It is a structural element for bones, an essential mediator of excitation-contraction coupling, and a universal...
19.
Fiander M, Stifani N, Nichols M, Akay T, Robertson G
Behav Brain Res
. 2016 Sep;
317:95-108.
PMID: 27639322
The preclinical selection of therapeutic candidates for progressive multiple sclerosis (MS) would be aided by the development of sensitive behavioural measures that accurately reflect the impact of autoimmune-mediated spinal cord...
20.
Profitt M, Deurveilher S, Robertson G, Rusak B, Semba K
Schizophr Bull
. 2016 Mar;
42(5):1207-15.
PMID: 26940700
Disruption of sleep/wake cycles is common in patients with schizophrenia and correlates with cognitive and affective abnormalities. Mice deficient in stable tubule only polypeptide (STOP) show cognitive, behavioral, and neurobiological...