George P Tuszynski
Overview
Explore the profile of George P Tuszynski including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
636
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Recent Articles
1.
Zheng X, Chang F, Rong Y, Tuszynski G
Exp Mol Pathol
. 2022 Feb;
125:104751.
PMID: 35122807
We have identified the novel protein GASP-1 (G protein coupled receptor-associated sorting protein 1) that appears to be a universal cancer marker and the expression of which in tumor tissue...
2.
Sharma M, Tuszynski G, Blackman M, Sharma M
Cancer Lett
. 2016 Jan;
373(1):27-35.
PMID: 26797420
There is considerable direct evidence that calcium binding protein ANX A2 is a potential target for treating aggressive breast cancer. The most compelling data are based on the finding of...
3.
Tuszynski G, Rothman V
Exp Mol Pathol
. 2013 Sep;
95(3):249-54.
PMID: 24036285
Acute myeloid leukemia (AML) is a malignant proliferative disorder in which leukemic cells fail to terminally differentiate and accumulate in the blood and bone marrow. Standard AML therapy requires intensive...
4.
Zheng X, Chang F, Zhang X, Rothman V, Tuszynski G
Exp Mol Pathol
. 2012 Apr;
93(1):111-5.
PMID: 22483848
Using an innovative "2-D high performance liquid electrophoresis" (2-D HPLE) technology we identified that a specific fragment of G-protein coupled receptor-associated sorting protein 1 (GASP-1) was present in the sera...
5.
Tuszynski G, Rothman V, Zheng X, Gutu M, Zhang X, Chang F
Exp Mol Pathol
. 2011 Jul;
91(2):608-13.
PMID: 21791203
An innovative "2-D high performance liquid electrophoresis" (2-D HPLE) technology was used to identify serum biomarkers associated with the early stage of breast cancer in addition to other more advanced...
6.
Godek J, Sargiannidou I, Patel S, Hurd L, Rothman V, Tuszynski G
Exp Mol Pathol
. 2011 Jan;
90(3):244-51.
PMID: 21241690
Angiocidin, a tumor-associated peptide, has been previously shown to inhibit tumor progression by blocking angiogenesis. We now show that angiocidin has a direct inhibitory effect on tumor cell proliferation. MDA-MB-231...
7.
Willis A, Sadowitz B, Fuse S, Maier K, Lee T, Wang X, et al.
Vasc Endovascular Surg
. 2011 Jan;
45(1):55-62.
PMID: 21193465
Background: Thrombospondin 1 (TSP-1), fibronectin (Fn), and vitronectin (Vn) promote vascular smooth muscle cell (VSMC) chemotaxis through a variety of second messenger systems, including Ras, ERK1/2, and p38. Hypothesis: Ras,...
8.
John A, Rothman V, Tuszynski G
J Oncol
. 2010 Jul;
2010:645376.
PMID: 20631908
Thrombospondin-1 (TSP-1) is involved in a variety of different cellular processes including cell adhesion, tumor progression, and angiogenesis. This paper reports the novel finding that TSP-1 upregulates integrin alpha6 subunit...
9.
LHeureux D, Rothman V, Tuszynski G
Exp Mol Pathol
. 2009 Nov;
88(1):15-25.
PMID: 19931242
Angiocidin, a matrix bound and tumor associated protein, has been shown to inhibit tumor progression and angiogenesis. We previously demonstrated that angiocidin binds to thrombospondin-1 and alpha2beta1 integrin. We now...
10.
John A, Hu X, Rothman V, Tuszynski G
Exp Mol Pathol
. 2009 Sep;
87(3):184-8.
PMID: 19747478
Thrombospondin-1 (TSP-1), a matrix-bound adhesive glycoprotein, has been shown to modulate tumor progression. We previously demonstrated that TSP-1 up-regulates matrix metalloproteinases MMP-2 and MMP-9. Our studies suggested that the balance...