George Kannourakis
Overview
Explore the profile of George Kannourakis including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
1041
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Recent Articles
1.
Ahmady F, Sharma A, Achuthan A, Kannourakis G, Luwor R
Cells
. 2025 Mar;
14(5).
PMID: 40072074
Several immunoregulatory or immune checkpoint receptors including T cell immunoglobulin and mucin domain 3 (TIM-3) have been implicated in glioblastoma progression. Rigorous investigation over the last decade has elucidated TIM-3...
2.
Wesley T, Escalona R, Kannourakis G, Ahmed N
Cancers (Basel)
. 2024 Dec;
16(23).
PMID: 39682273
Epithelial ovarian cancer is aggressive and causes high mortality among women worldwide. Members of the plakin family are essential to maintain cytoskeletal integrity and key cellular processes. In this study...
3.
Reduced T and NK Cell Activity in Glioblastoma Patients Correlates with TIM-3 and BAT3 Dysregulation
Ahmady F, Curpen P, Perriman L, Fonseca Teixeira A, Wu S, Zhu H, et al.
Cells
. 2024 Nov;
13(21.
PMID: 39513882
Inhibitory receptors are critical for regulating immune cell function. In cancer, these receptors are often over-expressed on the cell surface of T and NK cells, leading to reduced anti-tumor activity....
4.
Polash S, Poddar A, Ahmady F, Kannourakis G, Jayachandran A, Shukla R
ACS Appl Bio Mater
. 2024 Nov;
7(11):7635-7645.
PMID: 39497260
The zeolitic imidazolate framework (ZIF) is one of the most explored metal-organic-framework-based systems for nucleic acid delivery to cancer cells. Current nucleic acid delivery tools exhibit several drawbacks, such as...
5.
Poddar A, Ahmady F, Prithviraj P, Luwor R, Shukla R, Polash S, et al.
Prog Mol Biol Transl Sci
. 2024 Sep;
208:161-183.
PMID: 39266181
Cell and gene therapy are innovative biomedical strategies aimed at addressing diseases at their genetic origins. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) systems have become a groundbreaking tool in...
6.
Poddar A, Ahmady F, Rao S, Sharma R, Kannourakis G, Prithviraj P, et al.
J Biomed Sci
. 2024 Feb;
31(1):23.
PMID: 38395880
Pregnancy associated plasma protein-A (PAPP-A) plays an integral role in breast cancer (BC), especially triple negative breast cancer (TNBC). This subtype accounts for the most aggressive BC, possesses high tumor...
7.
Stuart S, Curpen P, Gomes A, Lan M, Nie S, Williamson N, et al.
Brain Sci
. 2024 Jan;
14(1).
PMID: 38248304
Glioblastoma is highly proliferative and invasive. However, the regulatory cytokine networks that promote glioblastoma cell proliferation and invasion into other areas of the brain are not fully defined. In the...
8.
Park S, Christo S, Wells A, Gandolfo L, Zaid A, Alexandre Y, et al.
Science
. 2023 Nov;
382(6674):1073-1079.
PMID: 38033053
Skin-resident CD8 T cells include distinct interferon-γ-producing [tissue-resident memory T type 1 (T1)] and interleukin-17 (IL-17)-producing (T17) subsets that differentially contribute to immune responses. However, whether these populations use common...
9.
Perriman L, Tavakolinia N, Jalali S, Li S, Hickey P, Amann-Zalcenstein D, et al.
Sci Immunol
. 2023 Jul;
8(85):eabo4365.
PMID: 37450574
Vγ9Vδ2 T cells are the largest population of γδ T cells in adults and can play important roles in providing effective immunity against cancer and infection. Many studies have suggested...
10.
Ciardiello F, Bang Y, Cervantes A, Dvorkin M, Lopez C, Metges J, et al.
Cancer Med
. 2023 Jun;
12(12):13145-13154.
PMID: 37260158
Background: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) are approved for the treatment of various solid tumors. In gastric cancer, genes commonly harbor mutations in the homologous recombination DNA repair pathway,...