George F Heine
Overview
Explore the profile of George F Heine including associated specialties, affiliations and a list of published articles.
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8
Citations
206
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Recent Articles
1.
Arora M, Zhang J, Heine G, Ozer G, Liu H, Huang K, et al.
Nucleic Acids Res
. 2012 Sep;
40(20):10187-202.
PMID: 22941662
We analyzed modification of chromatin by ubiquitination in human cells and whether this mark changes through the cell cycle. HeLa cells were synchronized at different stages and regions of the...
2.
Liu H, Zhang J, Heine G, Arora M, Ozer H, Onti-Srinivasan R, et al.
Nucleic Acids Res
. 2012 Sep;
40(20):10172-86.
PMID: 22941651
SUMOylation of transcription factors and chromatin proteins is in many cases a negative mark that recruits factors that repress gene expression. In this study, we determined the occupancy of Small...
3.
Heine G, Horwitz A, Parvin J
J Biol Chem
. 2008 Feb;
283(15):9555-61.
PMID: 18281289
Cellular DNA damage elicits the phosphorylation and ubiquitination of RNA polymerase II (RNAPII), leading to the global repression of transcription. In this report we show that there are at least...
4.
Heine G, Malik V, Dias A, Grotewold E
Mol Biotechnol
. 2007 Oct;
37(2):155-64.
PMID: 17914176
R2R3-MYB transcription factors play many important roles in higher plants including the regulation of secondary metabolism, the control of cell shape, and in the response to various stress conditions. In...
5.
Heine G, Parvin J
Sci STKE
. 2007 Jun;
2007(391):pe34.
PMID: 17579243
The ubiquitin ligase activity of the breast and ovarian cancer-associated tumor suppressor protein BRCA1, as part of a heterodimer with BARD1 (BRCA1-associated RING domain 1), is critical for its role...
6.
Horwitz A, Affar E, Heine G, Shi Y, Parvin J
Proc Natl Acad Sci U S A
. 2007 Apr;
104(16):6614-9.
PMID: 17420471
Loss of function of the tumor suppressor protein BRCA1 is responsible for a high percentage of familial and also sporadic breast cancers. Early work identified a stimulatory transcriptional coactivator function...
7.
Different mechanisms participate in the R-dependent activity of the R2R3 MYB transcription factor C1
Hernandez J, Heine G, Irani N, Feller A, Kim M, Matulnik T, et al.
J Biol Chem
. 2004 Sep;
279(46):48205-13.
PMID: 15347654
The R2R3 MYB transcription factor C1 requires the basic helix-loop-helix factor R as an essential co-activator for the transcription of maize anthocyanin genes. In contrast, the R2R3 MYB protein P1...
8.
Heine G, Hernandez J, Grotewold E
J Biol Chem
. 2004 Jul;
279(36):37878-85.
PMID: 15237103
Plant R2R3 MYB domain proteins comprise one of the largest known families of transcription factors. Discrete evolutionary steps have shaped the plant-specific R2R3 MYB family from the broadly distributed R1R2R3...