George Daaboul
Overview
Explore the profile of George Daaboul including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
495
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0
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Recent Articles
1.
Nouvel J, Bustos-Quevedo G, Prinz T, Masood R, Daaboul G, Gainey-Schleicher T, et al.
J Extracell Vesicles
. 2024 Oct;
13(10):e70008.
PMID: 39441012
Extracellular vesicles (EVs) are valuable targets for liquid biopsy. However, attempts to introduce EV-based biomarkers into clinical practice have not been successful to the extent expected. One of the reasons...
2.
Gokulnath P, Spanos M, Lehmann H, Sheng Q, Rodosthenous R, Chaffin M, et al.
Circulation
. 2024 Apr;
149(14):1147-1149.
PMID: 38557125
No abstract available.
3.
Ruan S, Rody Jr W, Patel S, Hammadi L, Martin M, de Faria L, et al.
Extracell Vesicles Circ Nucl Acids
. 2023 Nov;
4(3):518-529.
PMID: 37936884
Aim: Receptor activator of nuclear factor-kappa B (RANK)-containing extracellular vesicles (EVs) bind RANK-Ligand (RANKL) on osteoblasts, and thereby simultaneously inhibit bone resorption and promote bone formation. Because of this, they...
4.
Castro-Cruz M, Hyka L, Daaboul G, Leblanc R, Meeussen S, Lembo F, et al.
Proc Natl Acad Sci U S A
. 2023 Sep;
120(38):e2310914120.
PMID: 37695903
Extracellular vesicles (EVs) are membrane-limited organelles mediating cell-to-cell communication in health and disease. EVs are of high medical interest, but their rational use for diagnostics or therapies is restricted by...
5.
Li X, La Salvia S, Liang Y, Adamiak M, Kohlbrenner E, Jeong D, et al.
Circulation
. 2023 Jul;
148(5):405-425.
PMID: 37409482
Background: Adeno-associated virus (AAV) has emerged as one of the best tools for cardiac gene delivery due to its cardiotropism, long-term expression, and safety. However, a significant challenge to its...
6.
Gokulnath P, Spanos M, Lehmann H, Sheng Q, Rodosthenous R, Chaffin M, et al.
medRxiv
. 2023 Mar;
PMID: 36865094
Background: Acute decompensation is associated with increased mortality in heart failure (HF) patients, though the underlying etiology remains unclear. Extracellular vesicles (EVs) and their cargo may mark specific cardiovascular physiologic...
7.
Kaur S, Livak F, Daaboul G, Anderson L, Roberts D
J Extracell Vesicles
. 2022 Sep;
11(9):e12265.
PMID: 36107309
CD47 regulates the trafficking of specific coding and noncoding RNAs into extracellular vesicles (EVs), and the RNA contents of CD47 EVs differ from that of CD63 EVs released by the...
8.
Zhang W, Zhong W, Wang B, Yang J, Yang J, Yu Z, et al.
Dev Cell
. 2022 Jan;
57(3):329-343.e7.
PMID: 35085484
Tumor-derived extracellular vesicles (TEVs) suppress the proliferation and cytotoxicity of CD8 T cells, thereby contributing to tumor immune evasion. Here, we report that the adhesion molecule intercellular adhesion molecule 1...
9.
Deng F, Ratri A, Deighan C, Daaboul G, Geiger P, Christenson L
J Vis Exp
. 2022 Jan;
(179).
PMID: 35068480
Extracellular vesicles (EVs) are nanometer-sized vesicles with a lipid bilayer that are secreted by most cells. EVs carry a multitude of different biological molecules, including protein, lipid, DNA, and RNA,...
10.
Elmore Z, Havlik L, Oh D, Anderson L, Daaboul G, Devlin G, et al.
Nat Commun
. 2021 Oct;
12(1):6239.
PMID: 34716331
Adeno-associated viruses (AAV) rely on helper viruses to transition from latency to lytic infection. Some AAV serotypes are secreted in a pre-lytic manner as free or extracellular vesicle (EV)-associated particles,...