Patrick T Ellinor
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Explore the profile of Patrick T Ellinor including associated specialties, affiliations and a list of published articles.
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30293
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Recent Articles
1.
Choi S, Jurgens S, Xiao L, Hill M, Haggerty C, Sveinbjornsson G, et al.
Nat Genet
. 2025 Mar;
57(3):548-562.
PMID: 40050430
Atrial fibrillation (AF) is a prevalent and morbid abnormality of the heart rhythm with a strong genetic component. Here, we meta-analyzed genome and exome sequencing data from 36 studies that...
2.
Roselli C, Surakka I, S Olesen M, Sveinbjornsson G, Marston N, Choi S, et al.
Nat Genet
. 2025 Mar;
57(3):539-547.
PMID: 40050429
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-analysis of genome-wide association studies increased the power...
3.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
4.
Chaudhry S, Haj A, Ryu J, Jurgens S, Rodriguez Espada A, Wang X, et al.
JAMA
. 2025 Mar;
PMID: 40029645
Importance: Clinical decision-making in thrombotic disorders is impeded by long-standing uncertainty regarding the magnitude of venous and arterial thrombosis risk associated with low protein S. Population-scale multiomic datasets offer an...
5.
Marston N, Kamanu F, Melloni G, Schnitzler G, Hakim A, Ma R, et al.
Nat Med
. 2025 Feb;
PMID: 40011692
The role of endothelial cell (EC) dysfunction in contributing to an individual's susceptibility to coronary atherosclerosis and how low-density lipoprotein cholesterol (LDL-C) concentrations might modify this relationship have not been...
6.
Al-Alusi M, Friedman S, Kany S, Ramo J, Pipilas D, Singh P, et al.
NPJ Digit Med
. 2025 Feb;
8(1):120.
PMID: 39987256
Hypertension is a major risk factor for cardiovascular disease (CVD), yet blood pressure is measured intermittently and under suboptimal conditions. We developed a deep learning model to identify hypertension and...
7.
Ashburner J, Tack R, Khurshid S, Turner A, Atlas S, Singer D, et al.
Am Heart J
. 2025 Feb;
284:57-66.
PMID: 39978665
Background: Detection of undiagnosed atrial fibrillation (AF) after ischemic stroke through extended cardiac monitoring is important for preventing recurrent stroke. We evaluated whether a tool that displays clinically predicted AF...
8.
Lau E, Dsouza V, Zhao Y, Reeder C, Goldberg R, Economy K, et al.
medRxiv
. 2025 Feb;
PMID: 39974091
Importance: Cardiovascular disease (CVD) is the leading cause of maternal morbidity and mortality, however the contemporary burden and secular trends in pregnancy-related CV complications are not well characterized. Objective: We...
9.
Kany S, Al-Alusi M, Ramo J, Pirruccello J, Ajufo E, Churchill T, et al.
JACC Adv
. 2025 Feb;
4(3):101603.
PMID: 39954344
Background: Attaining guideline-recommended levels of physical activity is associated with substantially lower risk of cardiometabolic diseases. Objectives: Although physical activity commonly follows a weekend warrior pattern, in which most moderate-to-vigorous...
10.
Predicting Atrial Fibrillation After Stroke by Combining Polygenic Risk Scores and Clinical Features
Tack R, Tan B, Senff J, Prapiadou S, Kimball T, Khurshid S, et al.
Stroke
. 2025 Jan;
PMID: 39882610
Since treatment with anticoagulants can prevent recurrent strokes, identification of patients at risk for incident AF after stroke is crucial. We aimed to investigate whether the addition of AF polygenic...