Georg Gdynia
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Explore the profile of Georg Gdynia including associated specialties, affiliations and a list of published articles.
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22
Citations
587
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Recent Articles
1.
Scherr A, Mock A, Gdynia G, Schmitt N, Heilig C, Korell F, et al.
Cell Death Dis
. 2020 Oct;
11(10):875.
PMID: 33070156
Since metastatic colorectal cancer (CRC) is a leading cause of cancer-related death, therapeutic approaches overcoming primary and acquired therapy resistance are an urgent medical need. In this study, the efficacy...
2.
Scherr A, Jassowicz A, Pato A, Elssner C, Ismail L, Schmitt N, et al.
Int J Mol Sci
. 2020 Feb;
21(3).
PMID: 32046105
Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery...
3.
Elssner C, Goeppert B, Longerich T, Scherr A, Stindt J, Nanduri L, et al.
Gastroenterology
. 2018 Nov;
156(4):1190-1205.e14.
PMID: 30445013
Background & Aims: Cholangiocyte proliferation and ductular reaction contribute to the onset and progression of liver diseases. Little is known about the role of the transcription factor nuclear factor-κB (NF-κB)...
4.
Gdynia G, Robak T, Kopitz J, Heller A, Grekova S, Duglova K, et al.
EBioMedicine
. 2018 Jun;
32:125-133.
PMID: 29884457
A higher capacity to grow under hypoxic conditions can lead to a more aggressive behavior of tumor cells. Determining tumor activity under hypoxia may identify chronic lymphocytic leukemia (CLL) with...
5.
Veelken K, Schonland S, Gdynia G, Weber T, Blank N, Hegenbart U
Amyloid
. 2017 Nov;
25(1):68-69.
PMID: 29166802
No abstract available.
6.
Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G
Mol Cell Oncol
. 2016 Sep;
3(4):e1175538.
PMID: 27652323
Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein-a...
7.
Koehler B, Arslic-Schmitt T, Peccerella T, Scherr A, Schulze-Bergkamen H, Bruckner T, et al.
Alcohol Clin Exp Res
. 2016 Sep;
40(10):2094-2101.
PMID: 27581253
Background: Chronic alcohol consumption is a risk factor for colorectal cancer. The mechanisms by which ethanol (EtOH) exerts its carcinogenic effect on the colorectal mucosa are not clear and may...
8.
Scherr A, Gdynia G, Salou M, Radhakrishnan P, Duglova K, Heller A, et al.
Cell Death Dis
. 2016 Aug;
7(8):e2342.
PMID: 27537525
Colorectal cancer (CRC) is the second most common malignant neoplasia in women and men worldwide. The B-cell lymphoma 2 (Bcl-2) protein family is mainly known for its pivotal role in...
9.
Evers C, Kaufmann L, Seitz A, Paramasivam N, Granzow M, Karch S, et al.
Am J Med Genet A
. 2016 Mar;
170(6):1502-9.
PMID: 27016154
Intellectual disability (ID) with cerebellar ataxia comprises a genetically heterogeneous group of neurodevelopmental disorders. We identified a homozygous frameshift mutation in CWF19L1 (c.467delC; p.(P156Hfs*33)) by a combination of linkage analysis...
10.
Gdynia G, Sauer S, Kopitz J, Fuchs D, Duglova K, Ruppert T, et al.
Nat Commun
. 2016 Mar;
7:10764.
PMID: 26948869
The high-mobility group box 1 (HMGB1) protein has a central role in immunological antitumour defense. Here we show that natural killer cell-derived HMGB1 directly eliminates cancer cells by triggering metabolic...