Georg A Sprenger
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Explore the profile of Georg A Sprenger including associated specialties, affiliations and a list of published articles.
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62
Citations
718
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Recent Articles
1.
Schick S, Muller T, Takors R, Sprenger G
Eng Life Sci
. 2024 Oct;
24(10):e202400025.
PMID: 39391271
The L-tryptophan-derived purple pigment violacein (VIO) is produced in recombinant bacteria and studied for its versatile applications. Microbial synthetic co-cultures are gaining more importance as efficient factories for synthesizing high-value...
2.
Muller T, Schick S, Klemp J, Sprenger G, Takors R
Bioprocess Biosyst Eng
. 2024 Apr;
47(5):713-724.
PMID: 38627303
The concept of modular synthetic co-cultures holds considerable potential for biomanufacturing, primarily to reduce the metabolic burden of individual strains by sharing tasks among consortium members. However, current consortia often...
3.
Schoppel K, Trachtmann N, Korzin E, Tzanavari A, Sprenger G, Weuster-Botz D
Microb Cell Fact
. 2022 Oct;
21(1):201.
PMID: 36195869
Background: Although efficient L-tryptophan production using engineered Escherichia coli is established from glucose, the use of alternative carbon sources is still very limited. Through the application of glycerol as an...
4.
Jayaraman K, Trachtmann N, Sprenger G, Gohlke H
Appl Microbiol Biotechnol
. 2022 Sep;
106(19-20):6505-6517.
PMID: 36109385
The shikimate pathway delivers aromatic amino acids (AAAs) in prokaryotes, fungi, and plants and is highly utilized in the industrial synthesis of bioactive compounds. Carbon flow into this pathway is...
5.
Hildenbrand J, Sprenger G, Teleki A, Takors R, Jendrossek D
Microb Physiol
. 2022 Aug;
33(1):1-11.
PMID: 36041408
Polyphosphate kinases (PPKs) catalyze the reversible transfer of the γ-phosphate moiety of ATP (or of another nucleoside triphosphate) to a growing chain of polyphosphate (polyP). In this study, we describe...
6.
Schoppel K, Trachtmann N, Mittermeier F, Sprenger G, Weuster-Botz D
Bioprocess Biosyst Eng
. 2021 Sep;
44(12):2591-2613.
PMID: 34519841
L-tryptophan production from glycerol with Escherichia coli was analysed by perturbation studies and metabolic control analysis. The insertion of a non-natural shikimate transporter into the genome of an Escherichia coli...
7.
Guitart Font E, Sprenger G
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33348713
Phosphofructokinase (PFK) plays a pivotal role in glycolysis. By deletion of the genes , (encoding the two PFK isoenzymes), and (glucose 6-phosphate dehydrogenase) in K-12, a mutant strain (GL3) with...
8.
Khusainov I, Fatkhullin B, Pellegrino S, Bikmullin A, Liu W, Gabdulkhakov A, et al.
Nat Commun
. 2020 Apr;
11(1):1656.
PMID: 32245971
For the sake of energy preservation, bacteria, upon transition to stationary phase, tone down their protein synthesis. This process is favored by the reversible binding of small stress-induced proteins to...
9.
Moosmann D, Mokeev V, Kulik A, Osipenkov N, Kocadinc S, Ort-Winklbauer R, et al.
Appl Microbiol Biotechnol
. 2020 Feb;
104(8):3433-3444.
PMID: 32078019
L-phenylglycine (L-Phg) is a rare non-proteinogenic amino acid, which only occurs in some natural compounds, such as the streptogramin antibiotics pristinamycin I and virginiamycin S or the bicyclic peptide antibiotic...
10.
Palanisamy N, Degen A, Morath A, Ballestin J, Juraske C, Ozturk M, et al.
Nat Commun
. 2020 Jan;
11(1):276.
PMID: 31932594
An amendment to this paper has been published and can be accessed via a link at the top of the paper.