Geoffrey L Stephens
Overview
Explore the profile of Geoffrey L Stephens including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
1010
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tkaczyk C, Hamilton M, Datta V, Yang X, Hilliard J, Stephens G, et al.
PLoS One
. 2013 Oct;
8(10):e75103.
PMID: 24098366
An optimal host response against Staphylococcus aureus skin and soft tissue infections (SSTI) is dependent on IL-1β and IL-17 mediated abscess formation. Alpha toxin (AT), an essential virulence factor for...
2.
Ephrem A, Epstein A, Stephens G, Thornton A, Glass D, Shevach E
Eur J Immunol
. 2013 Jun;
43(9):2421-9.
PMID: 23722868
Treg cells express high levels of the glucocorticoid-induced tumor necrosis factor-related receptor (GITR), while resting conventional T (Tconv) cells express low levels that are increased upon activation. Manipulation of GITR/GITR-Ligand...
3.
Stephens G, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M
Eur J Immunol
. 2013 Apr;
43(7):1727-34.
PMID: 23568529
The aryl hydrocarbon receptor (AhR) is a key transcriptional regulator of Th17-cell differentiation. Although endogenous ligands have yet to be identified, evidence suggests that tryptophan metabolites can act as agonists...
4.
Karnell J, Karnell 3rd F, Stephens G, Rajan B, Morehouse C, Li Y, et al.
J Immunol
. 2011 Aug;
187(7):3603-12.
PMID: 21873529
Production of pathogenic Abs contributes to disease progression in many autoimmune disorders. The immunosuppressant agent mycophenolic acid (MPA) has shown clinical efficacy for patients with autoimmunity. The goal of these...
5.
IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease
Stephens G, Swerdlow B, Benjamin E, Coyle A, Humbles A, Kolbeck R, et al.
Eur J Immunol
. 2011 Mar;
41(4):952-62.
PMID: 21360526
IL-9 is a pleiotropic cytokine with key functions in tolerance and inflammation, and its expression is considered a hallmark of Th2-lineage cells. Here, we report that human and mouse Th17...
6.
Kolbeck R, Kozhich A, Koike M, Peng L, Andersson C, Damschroder M, et al.
J Allergy Clin Immunol
. 2010 Jun;
125(6):1344-1353.e2.
PMID: 20513525
Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for...
7.
Tough D, Sprent J, Stephens G
Curr Protoc Immunol
. 2008 Apr;
Chapter 4:4.7.1-4.7.9.
PMID: 18432992
This unit describes two methods used to determine the rate of turnover of T and B cells in vivo. In each method, this is accomplished by administering 5-bromo-2'-deoxyuridine (BrdU), a...
8.
Stephens G, Shevach E
Immunity
. 2007 Sep;
27(3):417-9.
PMID: 17892850
The Foxp3+ T cell lineage is thought to arise from self-specific precursors during development. By using a unique mouse model, Pacholczyk et al. (2007) present compelling evidence that self-specific cells...
9.
Stephens G, Andersson J, Shevach E
J Immunol
. 2007 May;
178(11):6901-11.
PMID: 17513739
Expression of the transcription factor FoxP3 is the hallmark of regulatory T cells that play a crucial role in dampening immune responses. A comparison of the development and phenotype of...
10.
Andersson J, Stefanova I, Stephens G, Shevach E
Int Immunol
. 2007 Mar;
19(4):557-66.
PMID: 17369190
Naturally occurring CD4(+)CD25(+) regulatory T cells (nT(R)) comprise a separate lineage of T cells that are essential for maintaining immunological tolerance to self. Here we demonstrate that the level of...