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Genta Akutsu

Explore the profile of Genta Akutsu including associated specialties, affiliations and a list of published articles. Areas
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1.
Haraguchi K, Shimada H, Kimura K, Akutsu G, Tanaka H, Abe H, et al.
ACS Med Chem Lett . 2013 Jun; 2(9):692-697. PMID: 23795238
The synthesis of 4'-ethynyl-2'-deoxy-4'-thioribonucleosides was carried out utilizing an electrophilic glycosidation in which 4-ethynyl-4-thiofuranoid glycal served as a glycosyl donor. Electrophilic glycosidation between and the silylated nucleobases (-acetylcytosine, -benzoyladenine and...
2.
Haraguchi K, Shimada H, Akutsu G, Kimura K, Tanaka H, Hamasaki T, et al.
Nucleic Acids Symp Ser (Oxf) . 2009 Sep; (53):97-8. PMID: 19749278
Synthesis of 4'-C-ethynyl-2'-deoxy-4'-thionucleosides was carried out based on electrophilic glycosidation using 4-C-ethynyl-4-thiofuranoid glycal. The glycal 15 was prepared as follows: oxidative cleavage of 6 with Pb(OAc)(4) forming the aldehyde 7,...