Genie Leung
Overview
Explore the profile of Genie Leung including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
5
Citations
1317
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0
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Recent Articles
1.
Oughtred R, Rust J, Chang C, Breitkreutz B, Stark C, Willems A, et al.
Protein Sci
. 2020 Oct;
30(1):187-200.
PMID: 33070389
The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.org) is an open-access database resource that houses manually curated protein and genetic interactions from multiple species including yeast, worm, fly, mouse,...
2.
Oughtred R, Stark C, Breitkreutz B, Rust J, Boucher L, Chang C, et al.
Nucleic Acids Res
. 2018 Nov;
47(D1):D529-D541.
PMID: 30476227
The Biological General Repository for Interaction Datasets (BioGRID: https://thebiogrid.org) is an open access database dedicated to the curation and archival storage of protein, genetic and chemical interactions for all major...
3.
Laufer R, Ng G, Liu Y, Patel N, Edwards L, Lang Y, et al.
Bioorg Med Chem
. 2014 Jul;
22(17):4968-97.
PMID: 25043312
TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to...
4.
Sampson P, Liu Y, Patel N, Feher M, Forrest B, Li S, et al.
J Med Chem
. 2014 May;
58(1):130-46.
PMID: 24867403
Polo-like kinase 4 (PLK4), a unique member of the polo-like kinase family of serine-threonine kinases, is a master regulator of centriole duplication that is important for maintaining genome integrity. Overexpression...
5.
Laufer R, Forrest B, Li S, Liu Y, Sampson P, Edwards L, et al.
J Med Chem
. 2013 Jul;
56(15):6069-87.
PMID: 23829549
The family of Polo-like kinases is important in the regulation of mitotic progression; this work keys on one member, namely Polo-like kinase 4 (PLK4). PLK4 has been identified as a...