Genevieve Pratviel
Overview
Explore the profile of Genevieve Pratviel including associated specialties, affiliations and a list of published articles.
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48
Citations
373
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Recent Articles
1.
Amrane S, Jaubert C, Bedrat A, Rundstadler T, Recordon-Pinson P, Aknin C, et al.
Nucleic Acids Res
. 2022 Dec;
50(21):12328-12343.
PMID: 36453997
G-quadruplexes (G4s) are four-stranded nucleic acid structures formed by the stacking of G-tetrads. Here we investigated their formation and function during HIV-1 infection. Using bioinformatics and biophysics analyses we first...
2.
Rundstadler T, Mothes E, Amrane S, Stigliani J, Verhaeghe P, Pratviel G
J Inorg Biochem
. 2021 Aug;
223:111551.
PMID: 34340058
G-quadruplex nucleic acids (G4s) are RNA and DNA secondary structures involved in the regulation of multiple key biological processes. They can be found in telomeres, oncogene promoters, RNAs, but also...
3.
Lavigne M, Helynck O, Rigolet P, Boudria-Souilah R, Nowakowski M, Baron B, et al.
Nucleic Acids Res
. 2021 Jul;
49(13):7695-7712.
PMID: 34232992
The multidomain non-structural protein 3 (Nsp3) is the largest protein encoded by coronavirus (CoV) genomes and several regions of this protein are essential for viral replication. Of note, SARS-CoV Nsp3...
4.
Pedron J, Boudot C, Brossas J, Pinault E, Bourgeade-Delmas S, Sournia-Saquet A, et al.
ACS Med Chem Lett
. 2020 Apr;
11(4):464-472.
PMID: 32292551
An antikinetoplastid pharmacomodulation study was conducted at position 6 of the 8-nitroquinolin-2(1)-one pharmacophore. Fifteen new derivatives were synthesized and evaluated against , , and , in parallel with a cytotoxicity...
5.
Laroui N, Coste M, Lichon L, Bessin Y, Gary-Bobo M, Pratviel G, et al.
Int J Pharm
. 2019 Aug;
569:118585.
PMID: 31376467
In this work, we implemented a supramolecular approach in order to combine photodynamic therapy (PDT) with gene therapy. We made use of a simple cationic guanidylated porphyrin (H‑PG) with the...
6.
Piedra-Arroni E, Makni F, Severac L, Stigliani J, Pratviel G, Bonduelle C
Polymers (Basel)
. 2019 Apr;
9(7).
PMID: 30970954
Polypeptide polymers can adopt natural protein secondary structures such as α-helices or β-sheets, and this unique feature is at the origin of some intriguing physico⁻chemical properties. In this work, we...
7.
Saad M, Guedin A, Amor S, Bedrat A, Tourasse N, Fayyad-Kazan H, et al.
Nucleic Acids Res
. 2019 Mar;
47(9):4363-4374.
PMID: 30923812
G-quadruplexes (G4) are non-canonical DNA and/or RNA secondary structures formed in guanine-rich regions. Given their over-representation in specific regions in the genome such as promoters and telomeres, they are likely...
8.
Pipier A, De Rache A, Modeste C, Amrane S, Mothes-Martin E, Stigliani J, et al.
Dalton Trans
. 2019 Mar;
48(18):6091-6099.
PMID: 30860519
Porphyrins represent a valuable class of ligands for G-quadruplex nucleic acids. Herein, we evaluate the binding of cationic porphyrins metallated with gold(iii) to G-quadruplex DNA and we compare it with...
9.
Zhou Q, Vu Ngoc B, Leszczynska G, Stigliani J, Pratviel G
Biomolecules
. 2018 Nov;
8(4).
PMID: 30441840
Oxidative RNA damage is linked to cell dysfunction and diseases. The present work focuses on the in vitro oxidation of 5-methylaminomethyl uridine (mnm⁵U), which belongs to the numerous post-transcriptional modifications...
10.
Pedron J, Boudot C, Bourgeade-Delmas S, Sournia-Saquet A, Paloque L, Rastegari M, et al.
ChemMedChem
. 2018 Sep;
13(20):2217-2228.
PMID: 30221468
An antikinetoplastid pharmacomodulation study at position 3 of the recently described hit molecule 3-bromo-8-nitroquinolin-2(1H)-one was conducted. Twenty-four derivatives were synthesised using the Suzuki-Miyaura cross-coupling reaction and evaluated in vitro on...